Evidence map›Paper›PMID 37337079›Full record

ArticleCommunications biology2023

Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases.

Victoria A Kleiner, Thierry O Fischmann, John A Howe, Douglas C Beshore, Michael J Eddins, Yan Hou, Todd Mayhood, Daniel Klein, Debbie D Nahas, Bob J Lucas and 5 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Victoria A Kleiner *Department of Virology, Immunology & Microbiology, National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.ORCID 0000-0001-9898-5706
Thierry O Fischmann *MRL, Merck & Co., Inc., Rahway, NJ, USA.ORCID 0000-0003-3406-3061
John A HoweMRL, Merck & Co., Inc., Rahway, NJ, USA.
Douglas C BeshoreMRL, Merck & Co., Inc., Rahway, NJ, USA.ORCID 0000-0001-9746-1863
Michael J EddinsMRL, Merck & Co., Inc., Rahway, NJ, USA.
Yan HouMRL, Merck & Co., Inc., Rahway, NJ, USA.
Todd MayhoodMRL, Merck & Co., Inc., Rahway, NJ, USA.
Daniel KleinMRL, Merck & Co., Inc., Rahway, NJ, USA.
Debbie D NahasMRL, Merck & Co., Inc., Rahway, NJ, USA.
Bob J LucasMRL, Merck & Co., Inc., Rahway, NJ, USA.
He XiMRL, Merck & Co., Inc., Rahway, NJ, USA.ORCID 0000-0002-4383-0157
Edward MurrayMRL, Merck & Co., Inc., Rahway, NJ, USA.
Daphne Y MaMRL, Merck & Co., Inc., Rahway, NJ, USA.
Krista GettyMRL, Merck & Co., Inc., Rahway, NJ, USA.
Rachel FearnsDepartment of Virology, Immunology & Microbiology, National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA. rfearns@bu.edu.ORCID 0000-0003-0783-7498
Merck & Co., Inc., Rahway, NJ, USA (United States) · USBoston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) are related RNA viruses responsible for severe respiratory infections and resulting disease in infants, elderly, and immunocompromised adults

Indexed as

MetapneumovirusRespiratory Syncytial Virus, HumanRespiratory Tract InfectionsAdultAgedHumansInfantRNA-Dependent RNA PolymeraseRNA, MessengerRNA-Dependent RNA PolymeraseRNA, Messenger

Identifiers

PMID37337079
PMCPMC10279679
OpenAlexW4381190431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.