ArticleAging clinical and experimental research2023
Overlapping status of frailty and fear of falling: an elevated risk of incident disability in community-dwelling older adults.
Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Association between frailty and adverse outcomes in patients undergoing maintenance hemodialysis: a systematic review and meta-analysis.Renal failure · 2024Pooled it
- The Applications of Artificial Intelligence for Assessing Fall Risk: Systematic Review.Journal of medical Internet research · 2024Pooled it
- The global prevalence of and risk factors for fear of falling among older adults: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Appreciating the complexity of frailty and user context in digital health intervention design: A qualitative study with personas.PloS one · 2026Article
- The impact of frailty and fear of falling on health-related quality of life in older adults with osteoporosis: a cross-sectional study.BMC geriatrics · 2025Article
- Associations between dimensions of physical activity (intensity, frequency, duration, and volume) and frailty among middle-aged and older Chinese adults.Journal of exercise science and fitness · 2025Article
- Intrinsic capacity and recent falls in adults 80 years and older living in the community: results from the ilSIRENTE Study.Aging clinical and experimental research · 2024Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough overlapping frailty and fear of falling (FoF) are likely to increase with population aging, the combined effect of frailty and FoF on incident disability is not yet well understood.
aimsThe purpose of this study is to examine whether frailty combined with FoF increased the risk of incident disability in older adults. Our secondary purpose was to clarify the synergistic effect of frailty and FoF on incident disability.
methodsThis is a prospective study. Participants were 9372 older adults (mean age 73.5 years). Frailty status was assessed using the Japanese Cardiovascular Health Study index, and FoF was measured using two closed questions. Incident disability was prospectively monitored by their long-term care insurance records.
resultsDuring the follow-up period (mean duration 23.4 months), 487 (5.2%) participants developed disability. The proportion of incident disability linearly increased according to FoF level regardless of baseline frailty status. Frail participants with FoF had a higher risk of incident disability than those with frailty only or neither (adjusted hazard ratio [HR] 2.63, 95% confidence interval [CI] 1.95-3.54). Frailty in combination with excessive FoF further increased the risk of incident disability (adjusted HR 4.30, 95% CI 2.56-7.23) although no synergistic effect was observed (relative excessive risk due to interaction 1.69, 95% CI - 0.55, 3.93).
conclusionThe overlapping status of frailty and FoF, especially excessive FoF, increases the risk of incident disability in older adults.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.