Evidence map›Paper›PMID 37337067›Full record

ArticleJournal of cancer research and clinical oncology2023

SARS-CoV-2 Omicron BA.5.2-infection and COVID-19 in persons with chronic myeloid leukaemia.

Fang Cheng, Hang Xiang, Robert Peter Gale, Siyi Chen, Jiao Qu, Hao Guo, Qiubai Li, Yanli Zhang, Weiming Li

Open access · greenAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Fang Cheng *Department of Pharmacy, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, 430022, China.
Hang Xiang *Department of Hematology, The Ventral Hospital of Enshi Tujia and Miao Autonomous Prefecture, Yichang, 443000, China.
Robert Peter GaleCentre for Haematology, Department of Immunology and Inflammation, Imperial College of Science, Technology and Medicine, London, UK.
Siyi ChenDepartment of Rheumatology and Immunology, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, 430022, China.
Jiao QuDepartment of Hematology, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, 430022, China.
Hao GuoDepartment of Hematology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, 450000, Henan, China.
Qiubai LiDepartment of Rheumatology and Immunology, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, 430022, China. qiubaili@hust.edu.cn.
Yanli ZhangDepartment of Hematology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, 450000, Henan, China. 13203729690@163.com.
Weiming LiDepartment of Hematology, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, 430022, China. lee937@126.com.
Union Hospital · CNHenan Cancer Hospital · CNHuazhong University of Science and Technology · CNImperial College London · GBThe Central Hospital of Enshi Tujia and Miao Autonomous Prefecture · CNUnion Hospital · CNWuhan Union Hospital · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA SARS-CoV-2 Omicron (BA.5.2) epidemic began in China in December, 2022 following stopping the zero COVID policy.

methodsWe studied features of the epidemic in 1,121 persons with chronic myeloid leukaemia (CML).

results1103 (98%) were in chronic, 10 in accelerated and 8 in acute phases. 834 (74%) became infected almost all of whom met criteria for COVID-19. The most common symptoms were fever (91%), cough (90%) and fatigue (82%). 42 infected persons were asymptomatic. Most people quarantined at home and self-medicated. 22 were hospitalized for COVID-19. At admission 5 had mild, 14, moderate and 3, severe/critical disease according to World Health Organization (WHO) criteria. 5 received respiratory assistance, 3 were admitted to the intensive care unit (ICU) and 1 in accelerated phase died from COVID-19. Co-variates associated with a risk of COVID-19 in SARS-CoV-2-infected subjects include age ≥ 65 years, higher education level and imatinib therapy.

conclusionIn conclusion, most SARS-CoV-2 Omicron BA.5.2 infections in persons with CML resulted in COVID-19 most of which cases are mild with only 1 death.

Indexed as

COVID-19Leukemia, Myelogenous, Chronic, BCR-ABL PositiveAgedFatigueHumansImatinib MesylateSARS-CoV-2Imatinib MesylateChronic myeloid leukaemiaCOVID-19Omicron BA.5.2SARS-CoV-2 Omicron

Identifiers

PMID37337067
PMCPMC11797113
OpenAlexW4381189948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.