Evidence map›Paper›PMID 37337034›Full record

ArticleVirchows Archiv : an international journal of pathology2023

Tertiary lymphoid structures in pulmonary metastases of microsatellite stable colorectal cancer.

Topias Karjula, Anne Niskakangas, Olli Mustonen, Iiris Puro, Hanna Elomaa, Maarit Ahtiainen, Teijo Kuopio, Jukka-Pekka Mecklin, Toni T Seppälä, Erkki-Ville Wirta and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Topias KarjulaTranslational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Aapistie 5a, 90220, Oulu, Finland. topias.karjula@oulu.fi.ORCID http://orcid.org/0000-0002-2342-6034
Anne NiskakangasTranslational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Aapistie 5a, 90220, Oulu, Finland.
Olli MustonenTranslational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Aapistie 5a, 90220, Oulu, Finland.
Iiris PuroTranslational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Aapistie 5a, 90220, Oulu, Finland.
Hanna ElomaaDepartment of Biological and Environmental Science, University of Jyväskylä, 40014, Jyväskylä, Finland.
Maarit AhtiainenDepartment of Pathology, Central Finland Health Care District, 40620, Jyväskylä, Finland.
Teijo KuopioDepartment of Biological and Environmental Science, University of Jyväskylä, 40014, Jyväskylä, Finland.
Jukka-Pekka MecklinDepartment of Education and Research, Central Finland Health Care District, 40620, Jyväskylä, Finland.
Toni T SeppäläFaculty of Medicine and Health Technology, Tampere University and TAYS Cancer Center, Tampere University Hospital, 33520, Tampere, Finland.
Erkki-Ville WirtaFaculty of Medicine and Health Technology, Tampere University and TAYS Cancer Center, Tampere University Hospital, 33520, Tampere, Finland.
Eero SihvoCentral Hospital of Central Finland, 40014, Jyväskylä, Finland.
Fredrik YannopoulosTranslational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Aapistie 5a, 90220, Oulu, Finland.
Olli HelminenTranslational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Aapistie 5a, 90220, Oulu, Finland.
Juha P VäyrynenTranslational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Aapistie 5a, 90220, Oulu, Finland.
Oulu University Hospital · FICentral Finland Health Care District · FITampere University Hospital · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates located at sites of chronic inflammation and recognized as prognosticators in several cancers. We aimed to analyse the prognostic effect of TLSs in colorectal cancer (CRC) pulmonary metastases and primary tumours, with a comparison to the CD3

Indexed as

Colorectal NeoplasmsLung NeoplasmsTertiary Lymphoid StructuresCD8-Positive T-LymphocytesHumansMicrosatellite RepeatsTumor MicroenvironmentMicrosatellite stable colorectal cancerPulmonary metastasisTertiary lymphoid structures

Identifiers

PMID37337034
PMCPMC10326136
OpenAlexW4381250714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.