ArticleScientific reports2023
A closer association between blood urea nitrogen and the probability of diabetic retinopathy in patients with shorter type 2 diabetes duration.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
- Serum long noncoding RNA human plasmacytoma variant translocation 1 (PVT1) expression levels in Egyptians type 2 diabetic patients and its correlation with severity of diabetic nephropathy.BMC endocrine disorders · 2026Article
- Association between the blood urea nitrogen to albumin ratio and all-cause mortality in critically ill patients with liver cirrhosis.BMC gastroenterology · 2026Article
- Endocan level and its association with glycemic and inflammatory indices in diabetic nephropathy.BMC endocrine disorders · 2026Article
- Prognostic value of blood urea nitrogen to albumin ratio in critically ill cirrhotic patients with ascites.Scientific reports · 2026Article
- Diabetic retinopathy: why some eyes suffer more - a focus on retina-specific risk factors and metabolic memory.Journal of translational medicine · 2026Review
- Determination of the relationship between raftlin, oxidative stress levels, and vitamin D receptor gene polymorphism in diabetic patients.Therapeutic advances in endocrinology and metabolism · 2026Article
- Increased blood urea nitrogen levels and compromised peripheral nerve function in patients with type 2 diabetes.World journal of diabetes · 2025Article
- Association between renal function and diabetic retinopathy: a mediation analysis of geriatric nutritional risk index.Diabetology & metabolic syndrome · 2025Article
- Exploring the value of blood urea nitrogen-to-albumin ratio in patients with acute pancreatitis admitted to the intensive care unit: a retrospective cohort study.Frontiers in nutrition · 2025Article
- L-shaped association between fasting blood glucose and urea in a non-diabetic population.Frontiers in nutrition · 2025Article
- Association Between Blood Urea Nitrogen/Albumin and the Incidence as Well as Progression of Type 2 Diabetes.Nutrients · 2024Article
- Nonlinear relationship between diabetes mellitus duration and diabetic retinopathy.Scientific reports · 2024Article
- Article
- Correlation of Albumin, Red Cell Distribution Width and Other Biochemical and Hematological Parameters with Glycated Hemoglobin in Diabetic, Prediabetic and Non-Diabetic Patients.International journal of molecular sciences · 2024Article
- Blood urea nitrogen to serum albumin ratio as a new prognostic indicator in type 2 diabetes mellitus patients with chronic kidney disease.Scientific reports · 2024Article
- Comprehensive machine learning models for predicting therapeutic targets in type 2 diabetes utilizing molecular and biochemical features in rats.Frontiers in endocrinology · 2024Article
- Association between blood urea nitrogen levels and diabetic retinopathy in diabetic adults in the United States (NHANES 2005-2018).Frontiers in endocrinology · 2024Article
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7 authors.
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Abstract
Blood urea nitrogen (BUN) is an indicator of renal function and catabolic status in human body. Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus (DM) and a serious threat to the vision of diabetic patients. We included 426 type 2 diabetic patients who visited the endocrinology department of Guangdong Provincial People's Hospital and received an ophthalmology consultation from December 2017 to November 2018. The outcome was the probability of DR in participants. Multivariable logistics analysis was used to confirm the relationship between BUN and the probability of DR. And interaction tests were conducted to find the effects of DM duration on their association. A total of 167 of 426 patients with type 2 diabetes had DR, with a probability of 39.20%. After adjusting for potential confounders, a positive association between BUN and the probability of DR (OR = 1.12; 95% CI 1.03-1.21; P = 0.0107). And a test for interaction between DM duration and BUN on the probability of DR was significant (P = 0.0295). We suggested that in patients with type 2 diabetes, BUN was positively associated with the probability of DR and the association was influenced by DM duration.
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