Evidence map›Paper›PMID 37336832›Full record

ReviewInsights into imaging2023

Bizarre parosteal osteochondromatous proliferation: an educational review.

Salvatore Gitto, Francesca Serpi, Carmelo Messina, Domenico Albano, Andrea Di Bernardo, Elisabetta Armiraglio, Luca Cannavò, Simone Mazzoli, Alessandro Luzzati, Antonina Parafioriti and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Insights into imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. [Primary malignant bone tumours-part II].Radiologie (Heidelberg, Germany) · 2026
    Review
  8. Article
  9. Bizarre Parosteal Osteochondromatous Proliferation (BPOP) of the Hand.Journal of the Belgian Society of Radiology · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Salvatore GittoIRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy.
Francesca SerpiDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Milan, Italy.
Carmelo MessinaIRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy.
Domenico AlbanoIRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy.
Andrea Di BernardoPathology Department, ASST Pini-CTO, Milan, Italy.
Elisabetta ArmiraglioPathology Department, ASST Pini-CTO, Milan, Italy.
Luca CannavòIRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy.
Simone MazzoliIRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy.
Alessandro LuzzatiIRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy.
Antonina ParafioritiPathology Department, ASST Pini-CTO, Milan, Italy.
Luca Maria SconfienzaIRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy. io@lucasconfienza.it.ORCID http://orcid.org/0000-0003-0759-8431
Istituto Ortopedico Galeazzi · ITUniversity of Milan · ITIstituto Ortopedico Gaetano Pini · IT

Funding

Fondazione AIRC per la Ricerca sul Cancro Investigator Grant
6 · The paper itself

Abstract

Bizarre parosteal osteochondromatous proliferation (BPOP) is a surface-based bone lesion belonging to the group of benign chondrogenic tumors. The aim of this review is to familiarize the readers with imaging features and differential diagnosis of BPOP, also addressing pathological presentation and treatment options. The peak of incidence of BPOP is in the third and fourth decades of life, although it can occur at any age. Hands are the most common location of BPOP (55%), followed by feet (15%) and long bones (25%). On imaging, BPOP appears as a well-marginated mass of heterotopic mineralization arising from the periosteal aspect of the bone. Typical features of BPOP are contiguity with the underlying bone and lack of cortico-medullary continuity, although cortical interruption and medullary involvement have been rarely reported. Histologically, BPOP is a benign bone surface lesion characterized by osteocartilaginous proliferation with disorganized admixture of cartilage with bizarre features, bone and spindle cells. Differential diagnosis includes both benign-such as florid reactive periostitis, osteochondroma, subungual exostosis, periosteal chondroma and myositis ossificans-and malignant lesions-such as periosteal chondrosarcoma and surface-based osteosarcoma. Treatment consists of surgical resection. Local recurrences are common and treated with re-excision.Critical relevance statement Bizarre parosteal osteochondromatous proliferation is a benign mineralized mass arising from the periosteal aspect of bone cortex. Multi-modality imaging characteristics, pathology features and differential diagnosis are here highlighted to familiarize the readers with this entity and offer optimal patient care.

Indexed as

Bizarre parosteal osteochondromatous proliferationCartilaginous tumorNora lesionOsteochondromaPeriostitis

Identifiers

PMID37336832
PMCPMC10279628
OpenAlexW4381249619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.