Evidence map›Paper›PMID 37336809›Full record

ArticleBulletin of experimental biology and medicine2023

Therapeutic Efficacy and Migration of Mesenchymal Stem Cells after Intracerebral Transplantation in Rats with Experimental Ischemic Stroke.

D D Namestnikova, I L Gubskiy, E A Cherkashova, K K Sukhinich, P A Melnikov, A N Gabashvili, V V Kurilo, V P Chekhonin, L V Gubsky, K N Yarygin

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

D D NamestnikovaFederal Center of Brain Research and Neurotechnologies, Federal Medical-Biological Agency of Russia, Moscow, Russia.
I L GubskiyFederal Center of Brain Research and Neurotechnologies, Federal Medical-Biological Agency of Russia, Moscow, Russia. gubskiy.ilya@gmail.com.
E A CherkashovaFederal Center of Brain Research and Neurotechnologies, Federal Medical-Biological Agency of Russia, Moscow, Russia.
K K SukhinichV. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia.
P A MelnikovV. P. Serbsky National Medical Research Center of Psychiatry and Narcology, Ministry of Health of the Russian Federation, Moscow, Russia.
A N GabashviliNational Research Technology University "MISiS", Moscow, Russia.
V V KuriloPirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia.
V P ChekhoninPirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia.
L V GubskyFederal Center of Brain Research and Neurotechnologies, Federal Medical-Biological Agency of Russia, Moscow, Russia.
K N YaryginV. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia.
Pirogov Russian National Research Medical University · RUInstitute of Biomedical Chemistry · RUMinistry of Health of the Russian Federation · RUFederal Medical Research Centre for Psychiatry and Narcology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied therapeutic efficacy and migration characteristics of mesenchymal stem cells isolated from the human placenta after their intracerebral (stereotactic) administration to rats with the experimental ischemic stroke. It was shown that cell therapy significantly improved animal survival rate and reduced the severity of neurological deficit. New data on the migration pathways of transplanted cells in the brain were obtained.

Indexed as

Brain IschemiaIschemic StrokeMesenchymal Stem CellsMesenchymal Stem Cell TransplantationStrokeAnimalsBrainDisease Models, AnimalFemaleHumansInfarction, Middle Cerebral ArteryPregnancyRatscell therapyintracerebral administrationischemic strokemesenchymal stem cellsmiddle cerebral artery occlusion model

Identifiers

PMID37336809
OpenAlexW4381193595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.