Evidence map›Paper›PMID 37335925›Full record

ArticleThe British journal of surgery2023

Impact of in-hospital postoperative complications on quality of life up to 12 months after major abdominal surgery.

Candice L Downey, Jamie Bainbridge, David G Jayne, David M Meads

Open access · hybridAbstract read
In one paragraph

Article in The British journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Candice L DowneyLeeds Institute of Medical Research at St James's, Clinical Sciences Building, St James's University Hospital, University of Leeds, Leeds, UK.
Jamie BainbridgeAcademic Unit of Health Economics, School of Medicine, University of Leeds, Leeds, UK.
David G JayneLeeds Institute of Medical Research at St James's, Clinical Sciences Building, St James's University Hospital, University of Leeds, Leeds, UK.ORCID 0000-0002-8725-3283
David M MeadsAcademic Unit of Health Economics, School of Medicine, University of Leeds, Leeds, UK.
University of Leeds · GB

Funding

Health FoundationLeeds Hospitals CharityNational Institute for Health ResearchRoyal College of Anaesthetists,UK Research and Innovation (Research England)University College LondonUniversity College London Hospitals Surgical Outcomes Research Centre
6 · The paper itself

Abstract

backgroundPostoperative complications are common, but there are limited data regarding their implications on patients' quality of life. This study aimed to address this gap in the literature by analysing the impact of postoperative complications on patients' health-related quality of life.

methodsData from the Perioperative Quality Improvement Programme were analysed, and included patient-level data for 19 685 adults who underwent elective major abdominal procedures in England since 2016. Postoperative complications were graded using the Clavien-Dindo classification. Quality of life was assessed by responses to the EuroQol five-dimension five-levels-of-response (EQ-5D-5L™) questionnaire before surgery, and at 6 and 12 months after operation. Ordinal logistic regression was used to estimate the association between Clavien-Dindo grades and quality of life. Tobit and ordinary least squares regression analyses were used to estimate the quality-adjusted life-year (QALY) loss resulting from postoperative complications between admission and 12 months after surgery.

resultsAt 6 and 12 months after surgery, increasingly severe postoperative complications were significantly associated with poorer health-related quality of life. The effect of postoperative complications on quality of life was sustained until at least 12 months after operation. Between admission and 12 months after surgery, 0.012, 0.026, 0.033, and 0.086 QALYs were lost for those experiencing a grade I, II, III, or IV postoperative complication respectively.

conclusionPostoperative complications have a significant and sustained effect on patients' quality of life after surgery; this effect worsens as the severity of the complications increases.

Indexed as

AbdomenPostoperative ComplicationsQuality of LifeAdultAgedAged, 80 and overElective Surgical ProceduresEnglandFemaleHumansMaleMiddle AgedQuality-Adjusted Life YearsSurveys and QuestionnairesTime Factors

Identifiers

PMID37335925
PMCPMC10416679
OpenAlexW4381251526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.