Evidence map›Paper›PMID 37335433›Full record

ArticleRheumatology and therapy2023

Mortality Trends Among Patients with Rheumatoid Arthritis in Western Australia.

Khalid B Almutairi, Charles A Inderjeeth, David B Preen, Helen I Keen, Johannes C Nossent

Abstract read
In one paragraph

Article in Rheumatology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  8. First fracture in rheumatoid arthritis: analysis by fracture site, gender, age, and comorbidities.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khalid B AlmutairiSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Perth, WA, 6009, Australia. khalid.almutairi@uwa.edu.au.ORCID http://orcid.org/0000-0002-9246-7294
Charles A InderjeethSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Perth, WA, 6009, Australia.ORCID http://orcid.org/0000-0003-0535-963X
David B PreenSchool of Population and Global Health, University of Western Australia, Perth, WA, Australia.ORCID http://orcid.org/0000-0002-2982-2169
Helen I KeenSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Perth, WA, 6009, Australia.ORCID http://orcid.org/0000-0002-8469-2424
Johannes C NossentSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Perth, WA, 6009, Australia.ORCID http://orcid.org/0000-0002-2833-7997

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWith scarce comparative data on mortality in Australian patients with rheumatoid arthritis (RA), we investigated temporal changes in standardized mortality rates for patients with RA using longitudinal linked population-wide health data in Western Australia (WA) over the period 1980 to 2015.

methodsThe study included 17,125 patients with a first-time hospital contact for RA (ICD-10-AM M05.00-M06.99 and ICD-9-AM 714.00-714.99) in the study period. Standardized mortality rate ratios (SMRRs) for the RA cohort versus the WA general population was estimated using direct age standardization. We analyzed temporal trends over with dates and causes provided by the WA Death Registry.

resultsDuring 356,069 patient-years of follow-up, a total of 8955 (52%) deaths occurred in the RA cohort. The SMRR was 2.24 (95% CI 2.15-2.34) in males and 3.09 (95% CI 3.00-3.19) in females over the study period. SMRR decreased since 2000 to 1.59 (95% CI 1.39-1.81) for the period 2011-2015. Median survival was 26.80 years (95% CI 26.30-27.30), where age and comorbidity independently increased the risk of death. The leading causes of deaths were cardiovascular diseases (26.60%), cancer (16.80%), rheumatic diseases (5.80%), chronic pulmonary disease 491 (5.50%), dementia (3.00%), and diabetes 235 (2.6%).

conclusionsThe mortality rate in patients with RA in WA has decreased but remains 1.59-times higher than in community counterparts, suggesting that there is room for further improvement. Comorbidity is the main modifiable risk factor to further reduce mortality in patients with RA.

Indexed as

ArthritisDeath causesMortalityMortality ratesRheumatoidSurvival analysis

Identifiers

PMID37335433
PMCPMC10326173

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