Evidence map›Paper›PMID 37335394›Full record

ArticleJournal of physiology and biochemistry2023

Study of hydrogen sulfide biosynthesis in synovial tissue from diabetes-associated osteoarthritis and its influence on macrophage phenotype and abundance.

Natalia Lendoiro-Cino, Arianna Rodríguez-Coello, Anna Saborido, Elena F-Burguera, Jennifer A Fernández-Rodríguez, Rosa Meijide-Faílde, Francisco J Blanco, Carlos Vaamonde-García

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of physiology and biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Natalia Lendoiro-CinoGrupo de Investigación en Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), 15006, A Coruña, Spain.
Arianna Rodríguez-CoelloGrupo de Investigación en Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), 15006, A Coruña, Spain.
Anna SaboridoGrupo de Investigación en Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), 15006, A Coruña, Spain.
Elena F-BurgueraGrupo de Investigación en Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), 15006, A Coruña, Spain.
Jennifer A Fernández-RodríguezGrupo Envejecimiento e Inflamación, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), 15006, A Coruña, Spain.
Rosa Meijide-FaíldeGrupo de Terapia Celular y Medicina Regenerativa, Centro Interdisciplinar de Química e Bioloxía (CICA), Departamento de Fisioterapia, Medicina y Ciencias Biomédicas, Facultad de Ciencias da Saúde, Universidade da Coruña (UDC), 15006, A Coruña, Spain.
Francisco J BlancoGrupo de Investigación en Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), 15006, A Coruña, Spain.
Carlos Vaamonde-GarcíaGrupo de Investigación en Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), 15006, A Coruña, Spain. carlos.vaamonde.garcia@udc.es.ORCID http://orcid.org/0000-0001-8658-5502
Universidade da Coruña · ES

Funding

Instituto de Salud Carlos III PI19/01206Instituto de Salud Carlos III RETIC-RIER RD16/0012/0002Instituto de Salud Carlos III RICORS-REI RD21/0002/0009Xunta de Galicia ED431B 2020/55Xunta de Galicia IN607A 2021/7
6 · The paper itself

Abstract

Type 2 diabetes (DB) is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases remain unclear. Synovial macrophages from OA patients with DB present a marked pro-inflammatory phenotype. Since hydrogen sulphide (H

Indexed as

Diabetes Mellitus, Type 2Hydrogen SulfideOsteoarthritisHumansMacrophagesMorpholinesOrganothiophosphorus CompoundsPhenotypeGYY 4137Hydrogen SulfideMorpholinesOrganothiophosphorus CompoundsGlucose stressHeme oxygenase-1Hydrogen sulfideMacrophagesOsteoarthritisType 2 diabetes

Identifiers

PMID37335394
PMCPMC10338594
OpenAlexW4381191502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.