Evidence map›Paper›PMID 37335163›Full record

ReviewJournal of food and drug analysis2023

What nature has to offer: Opportunities for immuno-oncology.

Rubina Kousar, Cheng-Han Lin, Bbumba Patrick, Miao He, Dong-Chuan Wu, Xing-Guo Li

Abstract readReview
In one paragraph

Review in Journal of food and drug analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rubina KousarGraduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.
Cheng-Han LinGraduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.
Bbumba PatrickGraduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.
Miao HePhD Program in Cellular and Molecular Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Dong-Chuan WuGraduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.
Xing-Guo LiGraduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent rapid development of cancer therapy has come about with the paradigm shift from the traditional goal of targeting cancer cells themselves, to reprograming the immune tumor microenvironment. Accumulating evidence shows that compounds that target epigenetic regulation, called epidrugs, play a crucial role in mediating the immunogenicity of cancer cells and in reshaping antitumor immunity. A large body of literature has recognized natural compounds as epigenetic modulators for their immunomodulatory effects and anticancer potential. Unifying our understanding of the role of these biologically active compounds in immuno-oncology may open new avenues for more effective cancer therapies. In this review, we explore how natural compounds modulate the epigenetic machinery to shape antitumor immune response, highlighting the promise offered by the Mother Nature that could be exploited therapeutically to improve outcomes for cancer patients.

Indexed as

Epigenesis, GeneticNeoplasmsHumansImmunotherapyTumor Microenvironment

Identifiers

PMID37335163
PMCPMC10281724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.