Evidence map›Paper›PMID 37334918›Full record

ArticleRenal failure2023

Clinical significance of serum glucose to lymphocyte ratio as a prognostic marker in peritoneal dialysis patients.

Jiexin Chen, Ruiying Tang, Xiaojiang Zhan, Jihong Deng, Yanxia Zhang, Haibo Long, Fenfen Peng, Na Tian, Yueqiang Wen, Xiaoyang Wang and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jiexin ChenDepartment of Nephrology, Jiangmen Central Hospital, Jiangmen, China.
Ruiying TangDepartment of Nephrology, Jiangmen Central Hospital, Jiangmen, China.
Xiaojiang ZhanDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Jihong DengDepartment of Nephrology, Jiangmen Central Hospital, Jiangmen, China.
Yanxia ZhangDepartment of Nephrology, Jiangmen Central Hospital, Jiangmen, China.
Haibo LongDepartment of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Fenfen PengDepartment of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Na TianDepartment of Nephrology, General Hospital of Ningxia Medical University, Yinchuan, China.
Yueqiang WenDepartment of Nephrology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiaoyang WangDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiaoran FengDepartment of Nephrology, Jiujiang NO.1 people's Hospital, Jiujiang, China.
Ning SuDepartment of Hematology, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Xingming TangDepartment of Nephrology, DongGuan SongShan Lake Tungwah Hospital, DongGuan, China.
Xianfeng WuDepartment of Nephrology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong Univeristy, Shanghai, China.
Qian ZhouDepartment of Medical Statistics, Clinical Trials Unit, The First Affiliated Hospital, Sun Yat-sen Univeristy, Guangzhou, China.
Qingdong XuDepartment of Nephrology, Jiangmen Central Hospital, Jiangmen, China.ORCID 0000-0001-8755-7968

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe glucose-to-lymphocyte ratio (GLR), a glucose metabolism and systemic inflammatory response parameter, is associated with an adverse prognosis for various diseases. However, the association between serum GLR and prognosis in patients undergoing peritoneal dialysis (PD) is poorly understood.

methodsIn this multi-center cohort study, 3236 PD patients were consecutively enrolled between 1 January 2009 and 31 December 2018. Patients were divided into four groups according to the quartiles of baseline GLR levels (Q1: GLR ≤ 2.91, Q2:2.91 < GLR ≤ 3.91, Q3:3.91 < GLR < 5.59 and Q4: GLR ≥ 5.59). The primary endpoint was all-cause and cardiovascular disease (CVD) related mortality. The correlation between GLR and mortality was examined using Kaplan-Meier and multivariable Cox proportional analyses.

resultsDuring the follow-up period of 45.93 ± 29.01 months, 25.53% (826/3236) patients died, of whom 31% (254/826) were in Q4 (GLR ≥ 5.59). Multivariable analysis revealed that GLR was significantly associated with all-cause mortality (adjusted HR 1.02; CI 1.00 ∼ 1.04,

conclusionA higher serum GLR level is an independent prognostic factor for all-cause and CVD mortality in patients undergoing PD, suggesting that more attention should be paid to GLR.

Indexed as

Cardiovascular DiseasesPeritoneal DialysisClinical RelevanceCohort StudiesGlucoseHumansPrognosisProportional Hazards ModelsRetrospective StudiesGlucoseall-cause mortalitycardiovascular mortalityglucose to lymphocyte ratioPeritoneal dialysis

Identifiers

PMID37334918
PMCPMC10281343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.