The Use of Free Vascularized Fibula Graft in Spinal Reconstruction: A Comprehensive Systematic Review.

Reconstructive surgeons frequently face large structural abnormalities after spine resection. Unlike defects in the mandible or long bone, where a free vascularized fibular graft (FVFG) is a popular alternative for segmental osseous reconstruction, data on the use of an FVFG in the spine are still limited. The purpose of this study was to comprehensively describe and analyze the outcome of spinal reconstruction utilizing FVFG. Methods: The extensive search included the following databases: PubMed, ScienceDirect, Web of Science, Cumulative Index to Nursing and Allied Health Literature, and Cochrane for relevant studies published up to January 20, 2023, according to PRISMA 2020 guidelines. Demographic data, flap success, recipient vessels, and flap-related complications were evaluated. Results: We identified 25 eligible studies involving 150 patients, consisting of 82 men and 68 women. Spinal reconstruction utilizing FVFG is mostly reported in the case of spinal neoplasm, followed by spinal infection (osteomyelitis and spinal tuberculosis) and spinal deformities. The cervical spine is the most common vertebral defect reported in the studies. All studies summarized in the present study reported successful spinal reconstruction, while wound infection was the most reported postoperative complication after spinal reconstruction utilizing FVFG. Conclusions: The results of the current study highlight the ability and superiority of using FVFG in spinal reconstruction. Despite being technically challenging, this strategy provides enormous benefits to patients. However, a further additional large-scale study is required to corroborate these findings.