ArticleFrontiers in endocrinology2023
Association of baseline Life's Essential 8 score and trajectories with carotid intima-media thickness.
Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Association between cardiovascular health factors, carotid intima-media thickness and cardiovascular outcomes in primary prevention population for cardiovascular disease.American journal of preventive cardiology · 2026Article
- Cardiovascular Health Among Employees of a Brazilian Tertiary Hospital Assessed by the Life's Essential 8 Score: A Cross-Sectional Pilot Study.Journal of clinical medicine · 2026Article
- Sustained high Life's Essential 8 is associated with lower risk of cerebral small vessel disease: a community-based study.Frontiers in neurology · 2025Article
- Interacting and joint effects of triglyceride-glucose index and blood pressure on cardiovascular diseases risk: a prospective cohort study.Diabetology & metabolic syndrome · 2024Article
- Changes in Life's Essential 8 and risk of cardiovascular disease in Chinese people.European journal of public health · 2024Article
- Association between life's essential 8 and periodontitis: a population-based study.BMC oral health · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: We aimed to examine the association between the baseline Life's Essential 8 (LE8) score and LE8 score trajectories with the continuous carotid intima-media thickness (cIMT) as well as the risk of high cIMT. Methods: The Kailuan study has been an ongoing prospective cohort study since 2006. A total of 12,980 participants who completed the first physical examination and cIMT detection at follow-up without a history of CVD and missing data on the component of LE8 metrics in or before 2006 were finally included in the analysis. The LE8 score trajectories were developed from 2006 to 2010 using trajectory modeling of the SAS procedure Proc Traj. The measurement and result review of the cIMT were performed by specialized sonographers using standardized methods. According to quintiles of baseline LE8 score, participants were categorized into five groups: Results: A total of 12,980 participants were finally included in aim 1, and 8,758 participants met aim 2 of the association between LE8 trajectories and cIMT/high cIMT. Compared with the Conclusions: In summary, our study revealed that high baseline LE8 scores and LE8 score trajectories were associated with lower continuous cIMT and attenuated risk of high cIMT.
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