Evidence map›Paper›PMID 37334012›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2023

Serum Levels of Adropin Improve the Predictability of MELD and Child-Pugh Score in Cirrhosis: Results of Proof-of-Concept Clinical Trial.

Yotam Kolben, Ariel Kenig, Asa Kessler, Yuval Ishay, Sarah Weksler-Zangen, Mualem Eisa, Yaron Ilan

Open access · goldAbstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yotam KolbenFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Ariel KenigFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Asa KesslerFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Yuval IshayFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Sarah Weksler-ZangenFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Mualem EisaFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Yaron IlanFaculty of Medicine, Hebrew University, Jerusalem, Israel.
Hadassah Medical Center · ILHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adropin is a peptide that was suggested to have a role in cirrhosis. The present study aimed to determine the ability to use serum adropin levels to improve their prediction accuracy as an adjunct to the current scores. In a single-center, proof-of-concept study, serum adropin levels were determined in thirty-three cirrhotic patients. The data were analyzed in correlation with Child-Pugh and MELD-Na scores, laboratory parameters, and mortality. Adropin levels were higher among cirrhotic patients that died within 180 days (1,325.7 ng/dL vs. 870.3 ng/dL,

Indexed as

Intercellular Signaling Peptides and ProteinsLiver CirrhosisHumansPrognosisSeverity of Illness IndexEnho protein, humanIntercellular Signaling Peptides and ProteinsadropinChild-Pugh score (CPS)cirrhosisfibrosisMELD

Identifiers

PMID37334012
PMCPMC10274576
OpenAlexW4379231202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.