Trial reportDrug design, development and therapy2023
The Effect of Different Doses of Ciprofol in Patients with Painless Gastrointestinal Endoscopy.
Trial report in Drug design, development and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07294989 (Median Effective Concentration of Ciprofol and Its Correlation With Bispectral Index), which is not on this map. Cited by 32 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Median Effective Concentration of Ciprofol and Its Correlation With Bispectral Index: A Prospective Observational Study
Who cites it
32 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Optimal dosing of ciprofol for gastrointestinal endoscopy: a systematic review and network meta-analysis.BMC gastroenterology · 2025Pooled it
- Efficacy and safety of ciprofol versus propofol for anesthesia in patients undergoing gastrointestinal endoscope: a systematic review and meta-analysis of randomized controlled trials (RCT).BMC anesthesiology · 2025Pooled it
- The safety and efficacy of remimazolam, ciprofol, and propofol anesthesia in endoscopy: a systematic review and network meta-analysis.BMC anesthesiology · 2025Pooled it
- Safety and efficacy of ciprofol versus propofol for gastrointestinal endoscopy: a meta-analysis.BMC gastroenterology · 2025Pooled it
- Ciprofol Versus Propofol for Sedation in Gastrointestinal Endoscopy: A Systematic Review and Meta-Analysis in a Chinese Population.Drug design, development and therapy · 2025Pooled it
- The novel ciprofol versus propofol during gastroenteroscopy in Chinese patients: a meta-analysis.Frontiers in medicine · 2025Pooled it
- The efficacy of ciprofol versus propofol on anesthesia in patients undergoing endoscopy: a systematic review and meta-analysis of randomized controlled trials.BMC anesthesiology · 2024Pooled it
- Ciprofol versus Propofol Combined with Alfentanil for Respiratory Adverse Events in Overweight Patients Undergoing Painless Gastroscopy: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- Efficacy and Safety of Ciprofol versus Propofol for Tracheal Intubation in Pediatric Patients Undergoing Laparoscopic Hernia Repair: An Assessor-Blinded Randomised Controlled Trial.Drug design, development and therapy · 2026Trial
- The median Effective Dose (EDBMC anesthesiology · 2025Trial
- The effects of ciprofol on haemodynamics under general anaesthesia during thoracoscopic surgery: a randomised, double-blind, controlled trial.BMC anesthesiology · 2025Trial
- Effective dose of ciprofol combined with low-dose sufentanil for sedation of gastroscopy: a dose-finding study using a biased coin design.BMC anesthesiology · 2025Trial
- Efficacy and Safety of Ciprofol Alone versus Ciprofol with Fentanyl for Upper Gastrointestinal Endoscopy: A Randomized, Double-Blind, Controlled Trial.Drug design, development and therapy · 2025Trial
- Combined Use of Remimazolam and Ciprofol Reduces Hypoxemia and Shortens Recovery Time During Sedated Gastrointestinal Endoscopy.Drug design, development and therapy · 2025Trial
- Reinforcement learning based automated anesthesia system for gastrointestinal endoscopy with a multicenter randomized trial.NPJ digital medicine · 2026Article
- Exploring the median effective dose of ciprofol for anesthesia induction in patients with heart valve disease: a prospective, single-arm, single-centre study.BMC anesthesiology · 2026Article
- Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia.Children (Basel, Switzerland) · 2026Review
- Effects of ciprofol versus propofol sedation on hypoxaemia and hypotension in elderly patients undergoing bidirectional endoscopy: protocol for a randomized controlled trial.Frontiers in medicine · 2026Article
- Precision Sedation for Gastrointestinal Endoscopy in Older Adults: Brain Vulnerability and Recovery.Drug design, development and therapy · 2026Review
- Efficacy and safety of ciprofol versus propofol for sedation in hysteroscopy: a systematic review and meta-analysis.Therapeutic advances in drug safety · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Ciprofol is currently used for painless gastrointestinal endoscopy and anesthesia induction. However, whether it is superior to propofol and its optimal dose remains unknown. Methods: A total of 149 patients, 63 males and 86 females, aged 18-80 years, BMI 18-28 kg/m Results: Compared with group P, the time to fall asleep was significantly shortened, and the incidence of nausea and vomiting and injection pain was significantly lower in groups C2, C3 and C4 ( Conclusion: The appropriate dose of ciprofol for painless gastrointestinal endoscopy is more advantageous than propofol in hemodynamics and respiratory stability, with less injection pain and nausea and vomiting, which is worthy of clinical promotion.
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