Evidence map›Paper›PMID 37333851›Full record

ArticleFrontiers in cellular and infection microbiology2023

Metatranscriptomic analysis revealed

Sifen Lu, Yongzhao Zhou, Ya Hu, Jing Wang, Honghao Li, Yifei Lin, Denian Wang, Jinghong Xian, Shengmei Zhao, Jinmin Ma and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. [Comparative Analysis of Oral and Gut Microbiota Composition in Children Aged 3-5 Years With Different Body Mass Indexes in Urumqi].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Review
  8. The investigation of the role of oral-originatedFrontiers in microbiology · 2024
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Sifen LuPrecision Medicine Key Laboratory of Sichuan Province and Precision Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yongzhao ZhouDepartment of Integrated Care Management Center, Frontier Science Center of Disease Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Ya HuCenter of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China.
Jing WangPrecision Medicine Key Laboratory of Sichuan Province and Precision Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Honghao LiDepartment of Hospital Management, West China Hospital, Sichuan University, Chengdu, China.
Yifei LinPrecision Medicine Key Laboratory of Sichuan Province and Precision Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Denian WangPrecision Medicine Key Laboratory of Sichuan Province and Precision Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jinghong XianDepartment of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, China.
Shengmei ZhaoDepartment of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, China.
Jinmin MaBeijing Genomics Institution (BGI)-PathoGenesis Pharmaceutical Technology, Beijing Genomics Institution (BGI)-Shenzhen, Shenzhen, China.
Zhongyi ZhuBeijing Genomics Institution (BGI)-PathoGenesis Pharmaceutical Technology, Beijing Genomics Institution (BGI)-Shenzhen, Shenzhen, China.
Shengying YangDepartment of Computer and Software, Jincheng College of Chengdu, Chengdu, China.
Qinghui MengBeijing Milu Ecological Research Center, Beijing Research Institute of Science and Technology, Beijing, China.
Yulin KangInstitute of Environmental Information, Chinese Research academy of Environmental Sciences, Beijing, China.
Bojiang ChenPrecision Medicine Key Laboratory of Sichuan Province and Precision Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Weimin LiPrecision Medicine Key Laboratory of Sichuan Province and Precision Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Sichuan University · CNBGI Group (China) · CNChengdu Medical College · CNChinese Research Academy of Environmental Sciences · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Disease severity and prognosis of coronavirus disease 2019 (COVID-19) disease with other viral infections can be affected by the oropharyngeal microbiome. However, limited research had been carried out to uncover how these diseases are differentially affected by the oropharyngeal microbiome of the patient. Here, we aimed to explore the characteristics of the oropharyngeal microbiota of COVID-19 patients and compare them with those of patients with similar symptoms. Methods: COVID-19 was diagnosed in patients through the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by quantitative reverse transcription polymerase chain reaction (RT-qPCR). Characterization of the oropharyngeal microbiome was performed by metatranscriptomic sequencing analyses of oropharyngeal swab specimens from 144 COVID-19 patients, 100 patients infected with other viruses, and 40 healthy volunteers. Results: The oropharyngeal microbiome diversity in patients with SARS-CoV-2 infection was different from that of patients with other infections. Conclusion: The oropharyngeal microbiome characterization was different between SARS-CoV-2 infection and infections caused by other viruses.

Indexed as

COVID-19MicrobiotaCOVID-19 TestingHumansPrevotellaSARS-CoV-2SphingolipidsSphingolipidsCOVID-19metatranscriptomic sequencingoropharyngeal microbiomePrevotellaSARS-CoV-2 infectionsphingolipid metabolism

Identifiers

PMID37333851
PMCPMC10272425
OpenAlexW4379185392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.