Evidence map›Paper›PMID 37333795›Full record

ReviewRSC advances2023

A fruitful century for the scalable synthesis and reactions of biphenyl derivatives: applications and biological aspects.

Hajar A Ali, Mohamed A Ismail, Abd El-Aziz S Fouda, Eslam A Ghaith

Abstract readReview
In one paragraph

Review in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. An Isolated LithiumJournal of the American Chemical Society · 2025
    Article
  4. Article
  5. Article
  6. Kinetics and Mechanism of PPhJournal of the American Chemical Society · 2024
    Article
  7. Synthesis,Current medicinal chemistry · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hajar A AliChemistry Department, Faculty of Science, Mansoura University 35516 Mansoura Egypt Abdelghaffar@mans.edu.eg.
Mohamed A IsmailChemistry Department, Faculty of Science, Mansoura University 35516 Mansoura Egypt Abdelghaffar@mans.edu.eg.
Abd El-Aziz S FoudaChemistry Department, Faculty of Science, Mansoura University 35516 Mansoura Egypt Abdelghaffar@mans.edu.eg.
Eslam A GhaithChemistry Department, Faculty of Science, Mansoura University 35516 Mansoura Egypt Abdelghaffar@mans.edu.eg.ORCID https://orcid.org/0000-0003-4259-6802

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review provides recent developments in the current status and latest synthetic methodologies of biphenyl derivatives. Furthermore, this review investigates detailed discussions of several metalated chemical reactions related to biphenyl scaffolds such as Wurtz-Fittig, Ullmann, Bennett-Turner, Negishi, Kumada, Stille, Suzuki-Miyaura, Friedel-Crafts, cyanation, amination, and various electrophilic substitution reactions supported by their mechanistic pathways. Furthermore, the preconditions required for the existence of axial chirality in biaryl compounds are discussed. Furthermore, atropisomerism as a type of axial chirality in biphenyl molecules is discussed. Additionally, this review covers a wide range of biological and medicinal applications of the synthesized compounds involving patented approaches in the last decade corresponding to investigating the crucial role of the biphenyl structures in APIs.

Identifiers

PMID37333795
PMCPMC10274569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.