Evidence map›Paper›PMID 37333463›Full record

ArticleOxidative medicine and cellular longevity2023

Increased Iron Levels and Oxidative Stress Mediate Age-Related Impairments in Male and Female

Karen Kich Gomes, Ana Beatriz Dos Santos, Jaciana Sousa Dos Anjos, Luana Paganotto Leandro, Maria Takemura Mariano, Felipe Lima Pinheiro, Marcelo Farina, Jeferson Luis Franco, Thais Posser

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Karen Kich GomesOxidative Stress and Cell Signaling Research Group, Interdisciplinary Research Center on Biotechnology-CIPBIOTEC, Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil.ORCID https://orcid.org/0000-0002-3680-222X
Ana Beatriz Dos SantosOxidative Stress and Cell Signaling Research Group, Interdisciplinary Research Center on Biotechnology-CIPBIOTEC, Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil.ORCID https://orcid.org/0000-0001-5057-9979
Jaciana Sousa Dos AnjosOxidative Stress and Cell Signaling Research Group, Interdisciplinary Research Center on Biotechnology-CIPBIOTEC, Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil.ORCID https://orcid.org/0000-0003-3048-0159
Luana Paganotto LeandroDepartment of Chemistry, Post Graduate Program in Toxicological Biochemistry, Universidade Federal de Santa Maria, RS, Brazil.ORCID https://orcid.org/0000-0003-0560-624X
Maria Takemura MarianoOxidative Stress and Cell Signaling Research Group, Interdisciplinary Research Center on Biotechnology-CIPBIOTEC, Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil.ORCID https://orcid.org/0000-0003-0516-4381
Felipe Lima PinheiroPaleontology Laboratory, Federal University of Pampa, Campus São Gabriel, RS, Brazil.ORCID https://orcid.org/0000-0003-3354-914X
Marcelo FarinaDepartment of Biochemistry, Federal University of Santa Catarina, Florianopolis, 88040-900 Santa Catarina, Brazil.ORCID https://orcid.org/0000-0001-8255-8515
Jeferson Luis FrancoOxidative Stress and Cell Signaling Research Group, Interdisciplinary Research Center on Biotechnology-CIPBIOTEC, Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil.ORCID https://orcid.org/0000-0002-3874-8618
Thais PosserOxidative Stress and Cell Signaling Research Group, Interdisciplinary Research Center on Biotechnology-CIPBIOTEC, Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil.ORCID https://orcid.org/0000-0002-6491-5854
Universidade Federal do Pampa · BRUniversidade Federal de Santa Maria · BRUniversidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is characterized by a functional decline in the physiological functions and organic systems, causing frailty, illness, and death. Ferroptosis is an iron- (Fe-) dependent regulated cell death, which has been implicated in the pathogenesis of several disorders, such as cardiovascular and neurological diseases. The present study investigated behavioral and oxidative stress parameters over the aging of

Indexed as

Drosophila melanogasterOxidative StressAnimalsAntioxidantsFemaleGlutathioneIronLipid PeroxidationMaleReactive Oxygen SpeciesAntioxidantsGlutathioneIronReactive Oxygen Species

Identifiers

PMID37333463
PMCPMC10275690
OpenAlexW4379980032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.