Evidence map›Paper›PMID 37333348›Full record

ArticlebioRxiv : the preprint server for biology2025

Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population.

Gabriel Birzu, Harihara Subrahmaniam Muralidharan, Danielle Goudeau, Rex R Malmstrom, Daniel S Fisher, Devaki Bhaya

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Gabriel BirzuDepartment of Applied Physics, Stanford University.ORCID 0000-0003-3561-024X
Harihara Subrahmaniam MuralidharanDepartment of Computer Science, University of Maryland, College Park.
Danielle GoudeauDOE Joint Genome Institute, Lawrence Berkeley National Laboratory.
Rex R MalmstromDOE Joint Genome Institute, Lawrence Berkeley National Laboratory.ORCID 0000-0002-4758-7369
Daniel S FisherDepartment of Applied Physics, Stanford University.
Devaki BhayaDepartment of Plant Biology, Carnegie Institution for Science.ORCID 0000-0001-7965-4258

Funding

Algorithms and Software for the Assembly of Metagenomic DataR01AI100947 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI POP, MIHAI · 2013 to 2025
$7.4M
NIAID NIH HHS R01 AI100947
6 · The paper itself

Abstract

Bacterial species often undergo rampant recombination yet maintain cohesive genomic identity. Ecological differences can generate recombination barriers between species and sustain genomic clusters in the short term. But can these forces prevent genomic mixing during long-term coevolution? Cyanobacteria in Yellowstone hot springs comprise several diverse species that have coevolved for hundreds of thousands of years, providing a rare natural experiment. By analyzing more than 300 single-cell genomes, we show that despite each species forming a distinct genomic cluster, much of the diversity within species is the result of hybridization driven by selection, which has mixed their ancestral genotypes. This widespread mixing is contrary to the prevailing view that ecological barriers can maintain cohesive bacterial species and highlights the importance of hybridization as a source of genomic diversity.

Identifiers

PMID37333348
PMCPMC10274767

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.