In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
18 authors at 4 institutions in 2 countries.
Salvor RafnsdottirLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0009-0005-8446-2708 Kijin JangLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0009-0006-1181-1927 Sara Tholl HalldorsdottirLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0009-0008-5844-5447 Meghna VinodLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0009-0008-9057-6834 Arnhildur TomasdottirLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0009-0008-6154-7612 Katrin MöllerLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0000-0002-4720-8568 Katrin HalldorsdottirLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.
Tinna ReynisdottirLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0000-0001-5148-4744 Laufey Halla AtladottirLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0009-0007-5787-3987 Kristin Elisabet AllisonFaculty of Life and Environmental Sciences, University of Iceland; Reykjavik, Iceland.ORCID 0000-0002-5699-1945 Kevin OstacoloLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.
Jin HeDepartment of Biochemistry and Molecular Biology, College of Natural Science, Michigan State University; MI, USA.ORCID 0000-0001-8283-7952 Li ZhangMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine; Baltimore, MD, USA.ORCID 0000-0001-9526-3935 Frances J NorthingtonDivision of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine; Baltimore, MD, USA.ORCID 0000-0003-4557-2646 Erna MagnusdottirDepartment of Biomedical Science and Department of Anatomy, Faculty of Medicine, University of Iceland; Reykjavík, Iceland.
Raul Chavez-ValdezDivision of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine; Baltimore, MD, USA.ORCID 0000-0002-0788-8028 Kimberley Jade AndersonDepartment of Genetics and Molecular Medicine, Landspitali University Hospital; Reykjavik, Iceland.ORCID 0000-0003-0629-6343 Hans Tomas BjornssonLouma G. Laboratory of Epigenetic Research, Faculty of Medicine, University of Iceland; Reykjavik, Iceland.ORCID 0000-0001-6635-6753 University of Iceland · ISJohns Hopkins University · USReykjavík University · ISMichigan State University · US
Funding
Imaging Neonatal Hypoxic Ischemic InjuryR01HD074593 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FRANCES J NORTHINGTON, JIANGYANG ZHANG · 2013 to 2026
$6.8MElucidating factors affecting blood levels of tau and GFAP in adults at risk for neurodegenerationU01NS114144 · NINDS · MESO SCALE DIAGNOSTICS, LLC · PI STENGELIN, MARTIN · 2020 to 2024
$3.3MAdvanced therapeutic hypothermia efficacy network modeling in neonatal HIER01HD110091 · NICHD · JOHNS HOPKINS UNIVERSITY · PI EVERETT, ALLEN D, NORTHINGTON, FRANCES J · 2022 to 2025
$2.7MPrecision Medicine for Neonatal Hypoxic-Ischemic Encephalopathy: Combined Neuroimaging Clinical Approach to Link Phenotypes to PrognosisR01NS126549 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Kenichi Oishi · 2022 to 2026
$2.0MCholinergic neuron degeneration after HI: New target for delayed therapy of neonatal HI to improve Learning and Memory DeficitsR21NS123814 · NINDS · JOHNS HOPKINS UNIVERSITY · PI NORTHINGTON, FRANCES J · 2022 to 2023
$450kNICHD NIH HHS R01 HD074593NICHD NIH HHS R01 HD110091NINDS NIH HHS R01 NS126549NINDS NIH HHS R21 NS123814NINDS NIH HHS U01 NS114144
6 · The paper itselfAbstract
The mild hypothermia response (MHR) maintains organismal homeostasis during cold exposure and is thought to be critical for the neuroprotection documented with therapeutic hypothermia. To date, little is known about the transcriptional regulation of the MHR. We utilize a forward CRISPR-Cas9 mutagenesis screen to identify the histone lysine methyltransferase SMYD5 as a regulator of the MHR. SMYD5 represses the key MHR gene
Identifiers
PMID37333301
PMCPMC10274674
OpenAlexW4376618299
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