Evidence map›Paper›PMID 37333296›Full record

ArticlebioRxiv : the preprint server for biology2023

Functional characterization of helminth-associated Clostridiales reveals covariates of Treg differentiation.

Shushan Sargsian, Alannah Lejeune, Defne Ercelen, Wen-Bing Jin, Alan Varghese, P'ng Loke, Yvonne A L Lim, Chun-Jun Guo, Ken Cadwell

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Shushan SargsianDepartment of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Alannah LejeuneDepartment of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Defne ErcelenDivision of Gastroenterology and Hepatology, Department of Medicine, New York University Langone Health, New York, NY 10016, USA.
Wen-Bing JinJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.
Alan VargheseDepartment of Cell Biology, New York University Grossman School of Medicine, New York, NY 10016, USA.
P'ng LokeLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Yvonne A L LimDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
Chun-Jun GuoJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.
Ken CadwellDivision of Gastroenterology and Hepatology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104.
New York University · USCornell University · USNational Institutes of Health · USNYU Langone Health · USTranslational Therapeutics (United States) · USUniversity of Malaya · MY

Funding

INFECTIOUS DISEASES &BASIC MICROBIOLOGICAL MECHANISMST32AI007180 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEISER, JEFFREY NEAL · 1985 to 2022
$8.9M
Diabetes, Digestive, and Kidney Diseases Extramural ResearchR01DK093668 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Ken Hashigiwa Cadwell · 2011 to 2026
$7.3M
Redefining the role of autophagy in bacterial diseaseR01AI121244 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ken Hashigiwa Cadwell · 2017 to 2026
$5.6M
The role of autophagy gene Atg16L1 in allogeneic hematopoietic stem cell transplantation - Resubmission - 1R01HL123340 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CADWELL, KEN HASHIGIWA, VAN DEN BRINK, MARCEL R M · 2015 to 2022
$5.2M
Mechanisms of MRSA intestinal colonizationR01AI140754 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO · 2020 to 2024
$3.5M
Interactions between helminth colonization and the gut microbiotaR01AI130945 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CADWELL, KEN HASHIGIWA · 2018 to 2022
$3.3M
An integrative and generalizable approach to modulate microbiota small molecules in the hostDP2HD101401 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUO, CHUN-JUN · 2019 to 2019
$2.5M
Alternatively activated macrophages during helminth infectionR01AI133977 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TORRES, VICTOR J. · 2017 to 2021
$2.4M
Molecular mechanisms behind microbiota regulation of host amino acid and glucose homeostasisR01DK135816 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI Chun-Jun Guo · 2023 to 2026
$1.9M
Mechanisms of fungal involvement during intestinal diseaseR01DK124336 · NIDDK · UNIVERSITY OF UTAH · PI ROUND, JUNE LOUISE · 2020 to 2023
$1.8M
NHLBI NIH HHS R01 HL123340NIAID NIH HHS R01 AI121244NIAID NIH HHS R01 AI130945NIAID NIH HHS R01 AI133977NIAID NIH HHS R01 AI140754NIAID NIH HHS T32 AI007180NICHD NIH HHS DP2 HD101401NIDDK NIH HHS R01 DK093668NIDDK NIH HHS R01 DK124336NIDDK NIH HHS R01 DK135816
6 · The paper itself

Abstract

Parasitic helminths influence the composition of the gut microbiome. However, the microbiomes of individuals living in helminth-endemic regions are understudied. The Orang Asli, an indigenous population in Malaysia with high burdens of the helminth

Indexed as

bacterial enzymesClostridiahelminthimmune modulationmetabolitesmicrobiomeregulatory T cellsTrichuris

Identifiers

PMID37333296
PMCPMC10274677
OpenAlexW4379515450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.