ArticlemedRxiv : the preprint server for health sciences2023
Metformin reduces SARS-CoV-2 in a Phase 3 Randomized Placebo Controlled Clinical Trial.
Open access · greenAbstract readPreprint
In one paragraph
Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 13 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
- Updated by
Authors and funding
36 authors at 10 institutions in 1 country.
Carolyn T BramanteGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Kenneth B BeckmanGenomics Center, University of Minnesota, Minneapolis, MN.
Tanvi MehtaDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN.
Amy B KargerDepartment of Laboratory Medicine and Pathology, Medical School, University of Minnesota, Minneapolis, MN.
David J OddeDepartment of Biomedical Engineering University of Minnesota, Minneapolis, MN.
Christopher J TignanelliDepartment of Surgery, Medical School, University of Minnesota, Minneapolis, MN.
John B BuseEndocrinology, University of North Carolina, Chapel Hill, NC.
Darrell M JohnsonGenomics Center, University of Minnesota, Minneapolis, MN.
Ray H B WatsonGenomics Center, University of Minnesota, Minneapolis, MN.
Jerry J DanielGenomics Center, University of Minnesota, Minneapolis, MN.
David M LiebovitzGeneral Internal Medicine, Northwestern University, Chicago, IL.
Jacinda M NicklasGeneral Internal Medicine, University of Colorado, Denver, CO.
Kenneth CohenUnitedHealth Group, Optum Labs, Minnetonka, MN.
Michael A PuskarichEmergency Medicine, Hennepin County Medical Center, Minneapolis, MN.
Hrishikesh K BelaniDepartment of Medicine, Olive View - University of California, Los Angeles, CA.
Lianne K SiegelDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN.
Nichole R KlattDepartment of Surgery, Medical School, University of Minnesota, Minneapolis, MN.
Blake AndersonAtlanta Veterans Affairs Medical Center, Atlanta, Georgia; Department of Medicine, Emory University School of Medicine, Atlanta, GA.
Katrina M HartmanGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Via RaoGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Aubrey A HagenGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Barkha PatelGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Sarah L FennoGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Nandini AvulaGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Neha V ReddyGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Spencer M EricksonGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Regina D FrictonGeneral Internal Medicine, Northwestern University, Chicago, IL.
Samuel LeeGeneral Internal Medicine, Northwestern University, Chicago, IL.
Gwendolyn GriffithsGeneral Internal Medicine, University of Minnesota, Minneapolis, MN.
Matthew F PullenDivision of Infectious Diseases and International Medicine, University of Minnesota, Minneapolis, MN.
Jennifer L ThompsonDepartment of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN.
Nancy SherwoodDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN.
Thomas A MurrayDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN.
Michael R RoseDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN.
David R BoulwareDivision of Infectious Diseases and International Medicine, University of Minnesota, Minneapolis, MN.
Jared D HulingDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN.
University of Minnesota · USNorthwestern University · USUniversity of Minnesota Medical Center · USEmory University · USHennepin County Medical Center · USOptum (United States) · USUniversity of California, Los Angeles · USUniversity of Colorado Denver · USUniversity of North Carolina at Chapel Hill · USVanderbilt University Medical Center · US
Funding
ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7MOTA-21-015A Post-Acute Sequelae of SARS-CoV-2 Infection Initiative: NYU Langone Health Clinical Science Core, Data Resource Core, and PASC Biorepository CoreOT2HL161847 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GROSS, RACHEL SHARON, HORWITZ, LEORA · 2021 to 2025
$651.0MRe-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6MUniversity of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9MPilot & Feasibility ProgramP30DK124723 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Nicholette D. Allred · 2020 to 2026
$11.0MProject 2: Cell Migration in Mechanically Complex MicroenvironmentsU54CA210190 · NCI · UNIVERSITY OF MINNESOTA · PI ODDE, DAVID J. · 2016 to 2020
$10.0MProject 3P01CA254849 · NCI · UNIVERSITY OF MINNESOTA · PI ODDE, DAVID J. · 2021 to 2025
$9.4MInstitutional Career Development CoreKL2TR002492 · NCATS · UNIVERSITY OF MINNESOTA · PI INGBAR, DAVID H · 2018 to 2022
$6.3MStatistical Methods and Software for Multivariate Meta-analysisR01LM012982 · NLM · UNIVERSITY OF MINNESOTA · PI LIN, LIFENG, SIEGEL, LIANNE · 2019 to 2022
$1.3MTraining in Biostatistics for Heart, Lung and Blood Disease ResearchT32HL129956 · NHLBI · UNIVERSITY OF MINNESOTA · PI NEATON, JAMES DENNIS · 2016 to 2020
$1.1MSelf-weighing for Weight Management in Adolescents with ObesityK23DK124654 · NIDDK · UNIVERSITY OF MINNESOTA · PI BRAMANTE, CAROLYN T · 2021 to 2024
$801kIterative development and pilot testing of a mobile health intervention to increase postpartum weight loss in women at increased risk for cardiometabolic diseaseK23HL133604 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI NICKLAS, JACINDA MAWSON · 2016 to 2019
$769kNCATS NIH HHS KL2 TR002492NCATS NIH HHS UL1 TR002489NCATS NIH HHS UL1 TR002494NCI NIH HHS P01 CA254849NCI NIH HHS U54 CA210190NHLBI NIH HHS K23 HL133604NHLBI NIH HHS OT2 HL156812NHLBI NIH HHS OT2 HL161847NHLBI NIH HHS T32 HL129956NIDDK NIH HHS K23 DK124654NIDDK NIH HHS P30 DK124723NLM NIH HHS R01 LM012982NLM NIH HHS R21 LM012744
Abstract
Current antiviral treatment options for SARS-CoV-2 infections are not available globally, cannot be used with many medications, and are limited to virus-specific targets.
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What OpenQuestion holds
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.