Evidence map›Paper›PMID 37333211›Full record

ArticlebioRxiv : the preprint server for biology2024

Cryptococcosis, tuberculosis, and a kidney cancer fail to fit the atherosclerosis paradigm for foam cell lipid content.

Valentina Guerrini, Brendan Prideaux, Rehan Khan, Selvakumar Subbian, Yina Wang, Evita Sadimin, Siddhi Pawar, Rahul Ukey, Eric A Singer, Chaoyang Xue and 1 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Valentina Guerrini
Brendan Prideaux
Rehan Khan
Selvakumar SubbianORCID 0000-0003-2021-8632
Yina Wang
Evita Sadimin
Eric A Singer
Chaoyang Xue
Maria Laura GennaroORCID 0000-0003-4801-3567
Rutgers, The State University of New Jersey · USThe University of Texas Medical Branch at Galveston · US

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Chang S Chan · 1997 to 2026
$94.5M
New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
Foam cells as drug targets in tuberculosisR01HL149450 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GENNARO, MARIA LAURA, KARAKOUSIS, PETROS C · 2019 to 2022
$3.9M
Trained immunity and the regulation of anti-fungal defenseR01AI169769 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Amariliz Rivera, Chaoyang Xue · 2022 to 2026
$3.1M
Role of phospholipids in antifungal drug resistance in Cryptococcus neoformansR01AI155647 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Chaoyang Xue · 2022 to 2026
$2.8M
Cohort and biomarkers for COVID-19 severity, natural history, and reinfectionR01AI158911 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI BARRETT, EMILY S, BLASER, MARTIN J · 2021 to 2023
$2.6M
NCATS NIH HHS UL1 TR003017NCI NIH HHS P30 CA072720NHLBI NIH HHS R01 HL149450NIAID NIH HHS R01 AI155647NIAID NIH HHS R01 AI158911NIAID NIH HHS R01 AI169769
6 · The paper itself

Abstract

Foam cells are dysfunctional, lipid-laden macrophages associated with chronic inflammation of diverse origin. The long-standing paradigm that foam cells are cholesterol-laden derives from atherosclerosis research. We previously showed that, in tuberculosis, foam cells surprisingly accumulate triglycerides. Here, we utilized bacterial (

Identifiers

PMID37333211
PMCPMC10274805
OpenAlexW4380028385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.