ArticleResearch square2023
Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability.
Wolfgang Sadee, Ian H Cheeseman, Audrey Papp, Maciej Pietrzak, Michal Seweryn, Xiaofei Zhou, Shili Lin, Amanda M Williams, Mark D Wewers, Heather M Curry and 12 more
Open access · greenAbstract readPreprint
In one paragraphArticle in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 7 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
22 authors at 6 institutions in 3 countries.
Wolfgang SadeeThe Ohio State University.
Ian H CheesemanTexas Biomedical Research Institute.
Audrey PappThe Ohio State University.
Maciej PietrzakThe Ohio State University.
Michal SewerynUniversity of Łódź.
Xiaofei ZhouThe Ohio State University.
Shili LinThe Ohio State University.
Amanda M WilliamsThe Ohio State University.
Mark D WewersThe Ohio State University.
Heather M CurryQED Biosciences, Inc.
Hao ZhangUniversity of Texas at San Antonio.
Hong CaiUniversity of Texas at San Antonio.
Carine Kunsevi-KilolaStellenbosch University.
Happy TshivhulaStellenbosch University.
Gerhard WalzlStellenbosch University.
Blanca I RestrepoUniversity of Texas Rio Grande Valley, South Texas Diabetes and Obesity Institute.
Léanie KleynhansStellenbosch University.
Katharina RonacherStellenbosch University.
Yufeng WangUniversity of Texas at San Antonio.
Eusondia ArnettTexas Biomedical Research Institute.
Abul K AzadTexas Biomedical Research Institute.
Larry S SchlesingerTexas Biomedical Research Institute.
The Ohio State University · USStellenbosch University · ZATexas Biomedical Research Institute · USThe University of Texas at San Antonio · USThe University of Texas Rio Grande Valley · USUniversity of Łódź · PL
Funding
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7MTISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1MExpression Genetics in Drug TherapyU01GM092655 · NIGMS · OHIO STATE UNIVERSITY · PI SADEE, WOLFGANG · 2010 to 2014
$8.6MAltered immune-endocrine axis in type 2 diabetes and tuberculosis riskR01AI116039 · NIAID · STELLENBOSCH UNIVERSITY · PI KLEYNHANS, LEANIE, RESTREPO, BLANCA I · 2015 to 2019
$1.7MIllumina NovaSeq 6000 Sequencing SystemS10OD030311 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2021 to 2021
$600kNCI NIH HHS P30 CA054174NIAID NIH HHS R01 AI116039NIGMS NIH HHS U01 GM092655NIH HHS P51 OD011133NIH HHS S10 OD030311
6 · The paper itselfAbstract
Background: Results: Herein, we systematically analyze interactions of a virulent Conclusions: We observe large inter-individual differences in bacterial uptake and growth, with tenfold variation in
Indexed as
Alveolar MacrophagesGenomicsSystems BiologyTuberculosis
Identifiers
PMID37333188
PMCPMC10275041
OpenAlexW4379877566
What OpenQuestion holds
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LicenceCC BY
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