Evidence map›Paper›PMID 37333184›Full record

ArticlebioRxiv : the preprint server for biology2023

Macrophages modulate fibrosis during newt lens regeneration.

Georgios Tsissios, Anthony Sallese, J Raul Perez-Estrada, Jared A Tangeman, Weihao Chen, Byran Smucker, Sophia C Ratvasky, Erika Grajales-Esquivel, Arielle Martinez, Kimberly J Visser and 5 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Georgios TsissiosDepartment of Biology, Miami University, Oxford, OH, USA.
Anthony SalleseDepartment of Biology, Miami University, Oxford, OH, USA.
J Raul Perez-EstradaDepartment of Biology, Miami University, Oxford, OH, USA.
Jared A TangemanDepartment of Biology, Miami University, Oxford, OH, USA.
Weihao ChenCenter for Visual Sciences at Miami University, Oxford, OH, USA.
Byran SmuckerCenter for Visual Sciences at Miami University, Oxford, OH, USA.
Sophia C RatvaskyDepartment of Biology, Miami University, Oxford, OH, USA.
Erika Grajales-EsquivelDepartment of Biology, Miami University, Oxford, OH, USA.
Arielle MartinezDepartment of Biology, Miami University, Oxford, OH, USA.
Kimberly J VisserCRTD Center for Regenerative Therapies Dresden, Technische Universität Dresden, Dresden, Germany.
Alberto Joven ArausKarolinska Institute, Department of Cell and Molecular Biology, Stockholm, Sweden.
Hui WangCenter for Visual Sciences at Miami University, Oxford, OH, USA.
Andras SimonKarolinska Institute, Department of Cell and Molecular Biology, Stockholm, Sweden.
Maximina H YunCRTD Center for Regenerative Therapies Dresden, Technische Universität Dresden, Dresden, Germany.
Katia Del Rio-TsonisDepartment of Biology, Miami University, Oxford, OH, USA.
Miami University · USKarolinska Institutet · SEMax Planck Institute of Molecular Cell Biology and Genetics · DETechnische Universität Dresden · DE

Funding

On Determinants of Lens RegenerationR01EY027801 · NEI · MIAMI UNIVERSITY OXFORD · PI DEL RIO-TSONIS, KATIA · 2017 to 2019
$1.1M
Inflammation is a driver of newt lens regenerationR21EY033916 · NEI · MIAMI UNIVERSITY OXFORD · PI DEL RIO-TSONIS, KATIA · 2022 to 2023
$397k
In vivo imaging of newt lens regeneration: Novel molecular, cellular and functional insightsR21EY031865 · NEI · MIAMI UNIVERSITY OXFORD · PI DEL RIO-TSONIS, KATIA, WANG, HUI · 2020 to 2021
$383k
Elucidating the gene regulatory networks that drive neural regenerationF99NS129167 · NINDS · MIAMI UNIVERSITY OXFORD · PI TANGEMAN, JARED A · 2022 to 2022
$41k
NEI NIH HHS R01 EY027801NEI NIH HHS R21 EY031865NEI NIH HHS R21 EY033916NINDS NIH HHS F99 NS129167
6 · The paper itself

Abstract

Previous studies indicated that macrophages play a role during lens regeneration in newts, but their function has not been tested experimentally. Here we generated a transgenic newt reporter line in which macrophages can be visualized

Identifiers

PMID37333184
PMCPMC10274724
OpenAlexW4379389998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.