Evidence map›Paper›PMID 37332823›Full record

ArticleACS omega2023

Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies.

Arif Ali, Muhammad Ishaq Ali Shah, Chaoping Fu, Zubair Hussain, Muhammad Nasimullah Qureshi, Saira Farman, Zahida Parveen, Amir Zada, Saira Nayab, Perveen Fazil and 6 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Bioactive Flavonoids and Phenolic Acids ofCurrent drug discovery technologies · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Arif AliDepartment of Chemistry, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.
Muhammad Ishaq Ali ShahDepartment of Chemistry, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.ORCID https://orcid.org/0009-0000-3153-7554
Chaoping FuInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen 361021, P. R. China.
Zubair HussainNational Institute for Biotechnology and Genetic Engineering College, Pakistan Institute of Engineering and Applied Sciences, Faisalabad 44000, Pakistan.
Muhammad Nasimullah QureshiDepartment of Chemistry, University of Swabi, Anbar, Swabi 23561, Khyber Pakhtunkhwa, Pakistan.
Saira FarmanDepartment of Biochemistry, Abdul Wali Khan University, Mardan 23200, Pakistan.
Zahida ParveenDepartment of Biochemistry, Abdul Wali Khan University, Mardan 23200, Pakistan.ORCID https://orcid.org/0000-0003-3846-3513
Amir ZadaDepartment of Chemistry, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.
Saira NayabDepartment of Chemistry, Shaheed Benazir Bhutto University, Sheringal 18050, Upper Dir, Khyber Pakhtunkhwa,Pakistan.ORCID https://orcid.org/0000-0002-9014-1602
Perveen FazilDepartment of Chemistry, University of Karachi, Karachi 75270, Pakistan.
Muhammad AteeqDepartment of Chemistry, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.
Gauhar RehmanDepartment of Zoology, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.ORCID https://orcid.org/0000-0001-8059-9591
Mohammad NaeemDepartment of Chemistry, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.
Mohammad IbrahimDepartment of Chemistry, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.
Momin KhanDepartment of Chemistry, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.ORCID https://orcid.org/0000-0003-0936-5025
Waliullah KhanDepartment of Chemistry, Abdul Wali Khan University, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.
Abdul Wali Khan University Mardan · PKHuaqiao University · CNNational Institute for Biotechnology and Genetic Engineering · PKShaheed Benazir Bhutto University · PKUniversity of Karachi · PKUniversity of Swabi · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dihydropyrazole (1-22) derivatives were synthesized from already synthesized chalcones. The structures of all of the synthesized compounds were confirmed by elemental analysis and various spectroscopic techniques. Furthermore, the synthesized compounds were screened against α amylase as well as investigated for antioxidant activities. The synthesized compounds demonstrate good to excellent antioxidant activities with IC

Identifiers

PMID37332823
PMCPMC10268634
OpenAlexW4379230651

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.