Evidence map›Paper›PMID 37332807›Full record

ArticleACS omega2023

StackBRAF: A Large-Scale Stacking Ensemble Learning for BRAF Affinity Prediction.

Nur Fadhilah Syahid, Natthida Weerapreeyakul, Tarapong Srisongkram

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nur Fadhilah SyahidGraduate School in the Program of Pharmaceutical Chemistry and Natural Products, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Natthida WeerapreeyakulDivision of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Tarapong SrisongkramDivision of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID https://orcid.org/0000-0001-8512-5379
Khon Kaen University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The B-rapidly accelerated fibrosarcoma (BRAF) is a proto-oncogene that plays a vital role in cell signaling and growth regulation. Identifying a potent BRAF inhibitor can enhance therapeutic success in high-stage cancers, particularly metastatic melanoma. In this study, we proposed a stacking ensemble learning framework for the accurate prediction of BRAF inhibitors. We obtained 3857 curated molecules with BRAF inhibitory activity expressed as a predicted half-maximal inhibitory concentration value (pIC

Identifiers

PMID37332807
PMCPMC10268632
OpenAlexW4379054016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.