Evidence map›Paper›PMID 37332633›Full record

ArticleMovement disorders clinical practice2023

Premonitory Urge and Tic Severity, Comorbidities, and Quality of Life in Chronic Tic Disorders.

Valerie Brandt, Jana Essing, Ewgeni Jakubovski, Kirsten Müller-Vahl

Abstract read
In one paragraph

Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Valerie BrandtSchool of Psychology, Centre for Innovation in Mental health University of Southampton Southampton UK.ORCID https://orcid.org/0000-0002-3208-2659
Jana EssingClinic of Psychiatry, Social Psychiatry and Psychotherapy Hannover Medical School Hanover Germany.
Ewgeni JakubovskiClinic of Psychiatry, Social Psychiatry and Psychotherapy Hannover Medical School Hanover Germany.
Kirsten Müller-VahlClinic of Psychiatry, Social Psychiatry and Psychotherapy Hannover Medical School Hanover Germany.ORCID https://orcid.org/0000-0002-7181-7419

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tics are intimately associated with premonitory urges (PU) but knowledge about urges is still limited, with small sample sizes often limiting the generalizability of findings. Objectives: This study addressed the following open questions: (1) is tic severity associated with urge severity, (2) how common is relief, (3) which comorbidities are associated with urges, (4) are urges, tics, and comorbidities associated with lower quality of life, and (5) can complex and simple, motor and vocal tics be differentiated based on PU? Methods: N = 291 patients who reported a confirmed diagnosis of chronic primary tic disorder (age = 18-65, 24% female) filled out an online survey assessing demographic data, comorbid conditions, location, quality and intensity of PU, as well as quality of life. Every tic was recorded, and whether the patient experienced a PU, the frequency, intensity, and quality of that urge. Results: PU and tic severity were significantly associated, and 85% of urge-related tics were followed by relief. A diagnosis of attention deficit/hyperactivity disorder (ADHD) or depression, female gender, and older age increased the likelihood of experiencing PU, while more obsessive compulsive (OCD) symptoms and younger age were associated with higher urge intensities. PU, complex vocal tics, ADHD, OCD, anxiety, and depression were related to lower quality of life. Motor and vocal, complex and simple tics did not differ regarding PU intensity, frequency, and quality, or relief. Conclusions: The results shed light on the relationship between PU, tics, comorbidities, age, gender, and quality of life in tic disorders.

Indexed as

chronic tic disordercomorbiditypremonitory urge (PU)quality of lifeTourette syndrome

Identifiers

PMID37332633
PMCPMC10272904

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.