Evidence map›Paper›PMID 37332592›Full record

ReviewFrontiers in cardiovascular medicine2023

The role of monocytes in thrombotic diseases: a review.

Zhongyu Han, Qiong Liu, Hongpeng Li, Meiqi Zhang, Luling You, Yumeng Lin, Ke Wang, Qiaoyin Gou, Zhanzhan Wang, Shuwei Zhou and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 49 citations in OpenAlex.

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  17. The Immunologic Spectrum of Biostimulators and Its Clinical Importance.Plastic and reconstructive surgery. Global open · 2025
    Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Zhongyu HanSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Qiong LiuSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hongpeng LiSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Meiqi ZhangSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Luling YouSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yumeng LinEye School of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ke WangEye School of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Qiaoyin GouEye School of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Zhanzhan WangLianyungang Clinical College of Nanjing Medical University, Lianyungang, China.
Shuwei ZhouDepartment of Radiology, The First Hospital of Hunan University of Chinese Medicine, Changsha, China.
YiJin CaiSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lan YuanSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Haoran ChenScience and Education Department, Chengdu Xinhua Hospital, Chengdu, China.
Chengdu University of Traditional Chinese Medicine · CNFirst Affiliated Hospital of Hunan University of Traditional Chinese Medicine · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular and cerebrovascular diseases are the number one killer threatening people's life and health, among which cardiovascular thrombotic events are the most common. As the cause of particularly serious cardiovascular events, thrombosis can trigger fatal crises such as acute coronary syndrome (myocardial infarction and unstable angina), cerebral infarction and so on. Circulating monocytes are an important part of innate immunity. Their main physiological functions are phagocytosis, removal of injured and senescent cells and their debris, and development into macrophages and dendritic cells. At the same time, they also participate in the pathophysiological processes of pro-coagulation and anticoagulation. According to recent studies, monocytes have been found to play a significant role in thrombosis and thrombotic diseases of the immune system. In this manuscript, we review the relationship between monocyte subsets and cardiovascular thrombotic events and analyze the role of monocytes in arterial thrombosis and their involvement in intravenous thrombolysis. Finally, we summarize the mechanism and therapeutic regimen of monocyte and thrombosis in hypertension, antiphospholipid syndrome, atherosclerosis, rheumatic heart disease, lower extremity deep venous thrombosis, and diabetic nephropathy.

Indexed as

arterial thrombosisintravenous thrombolysismacrophagemonocytethrombotic diseases

Identifiers

PMID37332592
PMCPMC10272466
OpenAlexW4379229706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.