Evidence map›Paper›PMID 37332581›Full record

ReviewFrontiers in cardiovascular medicine2023

Novelties in the pharmacological approaches for chronic heart failure: new drugs and cardiovascular targets.

Michele Correale, Lucia Tricarico, Francesca Croella, Simona Alfieri, Francesco Fioretti, Natale Daniele Brunetti, Riccardo M Inciardi, Savina Nodari

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Michele CorrealeDepartment of Cardiothoracic, Policlinico Riuniti University Hospital, Foggia, Italy.
Lucia TricaricoDepartment of Cardiothoracic, Policlinico Riuniti University Hospital, Foggia, Italy.
Francesca CroellaDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Simona AlfieriDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Francesco FiorettiCardiology Section, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, ASST Spedali Civili Hospital and University of Brescia, Brescia, Italy.
Natale Daniele BrunettiDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Riccardo M InciardiCardiology Section, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, ASST Spedali Civili Hospital and University of Brescia, Brescia, Italy.
Savina NodariCardiology Section, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, ASST Spedali Civili Hospital and University of Brescia, Brescia, Italy.
University of Brescia · ITUniversity of Foggia · ITOspedali Riuniti di Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite recent advances in chronic heart failure (HF) management, the prognosis of HF patients is poor. This highlights the need for researching new drugs targeting, beyond neurohumoral and hemodynamic modulation approach, such as cardiomyocyte metabolism, myocardial interstitium, intracellular regulation and NO-sGC pathway. In this review we report main novelties on new possible pharmacological targets for HF therapy, mainly on new drugs acting on cardiac metabolism, GCs-cGMP pathway, mitochondrial function and intracellular calcium dysregulation.

Indexed as

cardiac metabolismCGMP pathwayheart failuremitochondrial functionnew drugstherapy targets

Identifiers

PMID37332581
PMCPMC10272855
OpenAlexW4379141684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.