Evidence map›Paper›PMID 37332500›Full record

ReviewFEMS microbes2022

Interactions of the bacteriome, virome, and immune system in the nose.

Matthew Flynn, Zinnia Lyall, Gwendolyn Shepherd, Osher Ngo Yung Lee, Ioannou Marianna Da Fonseca, Yijia Dong, Stuart Chalmers, Jamie Hare, Jack Thomson, Freya Millar

Open access · goldAbstract readReview
In one paragraph

Review in FEMS microbes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. The respiratory tract virome: unravelling the role of viral dark matter in respiratory health and disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  4. Review
  5. Diagnosing and engineering gut microbiomes.EMBO molecular medicine · 2024
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Matthew FlynnUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.ORCID https://orcid.org/0000-0002-0499-9777
Zinnia LyallUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.
Gwendolyn ShepherdUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.
Osher Ngo Yung LeeUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.ORCID https://orcid.org/0000-0001-6983-7157
Ioannou Marianna Da FonsecaUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.
Yijia DongUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.
Stuart ChalmersUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.
Jamie HareUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.
Jack ThomsonUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.
Freya MillarUniversity of Edinburgh, Medical School, College of medicine and vetinary medicine, 47 Little France Crescent, Edinrburgh EH16 4TJ, United Kingdom.
University of Edinburgh · GBNHS Greater Glasgow and Clyde · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence suggests that the nasal microbiome may influence host susceptibility to initial development and severity of respiratory viral infections. While not as extensively studied as the microbiota of the alimentary tract, it is now clearly established that the microbial composition of this niche is influenced by medical, social and pharmacological influences, predisposing some sub-populations to respiratory infections. The resulting specific microbial profiles may explain variance in susceptibility to viral infection. This review summaries the evolution and constituents of the commensal nasal microbiome; the bacterial-virus, bacterial-host and interbacterial interactions which potentiate disease; and considers the effects of interventions such as vaccination and probiotics.

Indexed as

bacteriacommensalnasal cavitynasopharynxrespiratoryviruses

Identifiers

PMID37332500
PMCPMC10117739
OpenAlexW4289856941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.