Evidence map›Paper›PMID 37332341›Full record

ReviewOpen access journal of contraception2023

A Brief History and Advancement of Contraceptive Multipurpose Prevention Technology (cMPT) Products.

Sarah Dohadwala, Joseph A Politch, Jessica H Barmine, Deborah J Anderson

Abstract readReview
In one paragraph

Review in Open access journal of contraception, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah DohadwalaDepartment of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Joseph A PolitchDepartment of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Jessica H BarmineDepartment of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Deborah J AndersonDepartment of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.

Funding

Project 3: Film Formulation, PK/PD and Safety Studies of ZB-06P50HD096957 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ANDERSON, DEBORAH J · 2019 to 2025
$12.9M
NICHD NIH HHS P50 HD096957
6 · The paper itself

Abstract

The high incidence of HIV and other sexually transmitted infections (STIs), and an unmet need for modern contraception resulting in a high unintended pregnancy rate, are major problems in reproductive health. The concept of multipurpose prevention technology (MPT) was introduced following the failure of several leading microbicide candidates to prevent human immunodeficiency virus type 1 (HIV-1) transmission in large clinical trials in the early 2000s. MPTs are defined as products designed to simultaneously prevent at least two of the following conditions: unintended pregnancy, HIV-1, or other major STIs. The goal of contraceptive MPT products (cMPTs) is to provide contraception and protection against one or more major STI pathogen (eg, HIV-1, herpes simplex virus (HSV) type 2,

Indexed as

contraceptivemicrobicidemultipurpose prevention technologysexually transmitted infection

Identifiers

PMID37332341
PMCPMC10276588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.