Evidence map›Paper›PMID 37331817›Full record

ArticleThe Journal of veterinary medical science2023

Diagnosis of rabies using reverse-transcription polymerase chain reaction on post-mortem skin tissue specimens of the nasolabial plate in a rabies suspected cow: a case study.

Anil Kumar Sharma, Parinita Prashar, Omesh Kumar Bharti, Riyesh Thachamvally, Rashmi Thakur, Naveen Kumar, Karuppusamy Shanmugasundaram, Harisankar Singha, Tarun Kumar Bhattacharya, Baldev Raj Gulati and 5 more

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Anil Kumar SharmaDepartment of Animal Husbandry, Himachal Pradesh, India.
Parinita PrasharDepartment of Animal Husbandry, Himachal Pradesh, India.
Omesh Kumar BhartiDepartment of Health and Family Welfare, Himachal Pradesh, India.
Riyesh ThachamvallyIndian Council of Agriculture Research-National Research Center on Equines (ICAR-NRCE), Hisar, India.
Rashmi ThakurDepartment of Animal Husbandry, Himachal Pradesh, India.
Naveen KumarIndian Council of Agriculture Research-National Research Center on Equines (ICAR-NRCE), Hisar, India.
Karuppusamy ShanmugasundaramIndian Council of Agriculture Research-National Research Center on Equines (ICAR-NRCE), Hisar, India.
Harisankar SinghaIndian Council of Agriculture Research-National Research Center on Equines (ICAR-NRCE), Hisar, India.
Tarun Kumar BhattacharyaIndian Council of Agriculture Research-National Research Center on Equines (ICAR-NRCE), Hisar, India.
Baldev Raj GulatiIndian Council of Agriculture Research-National Institute of Veterinary Epidemiology and Disease Informatics, Bengaluru, India.
Shrikrishna IsloorKVAFSU-CVA, Rabies Diagnostic Laboratory, WOAH Reference Laboratory for Rabies, Veterinary College, Bengaluru, India.
Ashok Kumar PandaDr. GC Negi College of Veterinary and Animal Sciences, Palampur, India.
Jyotsna SharmaAyush Department, Ayurvedic Health Centre, Himachal Pradesh, India.
Mankaran HaraShri Guru Ram Dass Institute of Medical Sciences and Research, Punjab, India.
Darryn KnobelRoss University School of Veterinary Medicine, Basseterre, Saint Kitts and Nevis.
National Research Centre on Equines · INGovernment Ayurvedic College and Hospital · INInstitute of Medical Sciences · INKarnataka Veterinary Animal and Fisheries Sciences University · INKerala Veterinary and Animal Sciences University · INNational Institute Of Veterinary Epidemiology And Disease Informatics · INRoss University School of Veterinary Medicine · KN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In India, rabies in cattle is under-reported. Religious sentiments hamper its diagnosis, discouraging post-mortem examination, particularly opening the cranium. Specimens of peripheral tissue innervated by the cranial nerves could potentially be used as alternative diagnostic specimens to the brain. Herein, we present a case study of a novel approach for diagnosing rabies in a cow suspected of having rabies, using skin tissue specimens of the nasolabial plate obtained post-mortem. Brain and nasolabial tissue specimens tested positive for rabies using conventional reverse-transcription polymerase chain reaction. This approach has been previously shown to have a high diagnostic sensitivity in animals. We encourage further studies with more nasolabial plate skin specimens for both post- and antemortem diagnosis of rabies in cattle.

Indexed as

Cattle DiseasesRabiesRabies virusAnimalsAutopsyBrainCattleFemaleReverse Transcriptase Polymerase Chain ReactionRNA, ViralRNA, Viraldiagnosisnasolabial platerabiesRT-PCRskin tissue

Identifiers

PMID37331817
PMCPMC10466064
OpenAlexW4381110711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.