Evidence map›Paper›PMID 37331780›Full record

ReviewSeminars in radiation oncology2023

The Promise and Future of Radiomics for Personalized Radiotherapy Dosing and Adaptation.

Rachel B Ger, Lise Wei, Issam El Naqa, Jing Wang

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Prognostic significance of the mEPE score in intermediate-risk prostate cancer patients undergoing ultrahypofractionated robotic SBRT.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Rachel B GerRadiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD.
Lise WeiDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI.
Issam El NaqaDepartment of Machine Learning, Moffitt Cancer Center and Research Institute, Tampa, FL.
Jing WangDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX.. Electronic address: Jing.Wang@UTSouthwestern.edu.
Johns Hopkins University · USMoffitt Cancer Center · USSouthwestern Medical Center · USUniversity of Michigan · US

Funding

Combined radiation acoustics and ultrasound imaging for real-time guidance in radiotherapyR37CA222215 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EL NAQA, ISSAM M. · 2018 to 2024
$3.5M
An Ionizing Radiation Acoustics Imaging (iRAI) Approach for guided Flash RadiotherapyR01CA266803 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI BORTFELD, THOMAS R., EL NAQA, ISSAM M. · 2022 to 2025
$3.3M
A Multifaceted Radiomics Model to Predict Cervical Lymph Node Metastasis for Involved Nodal Radiation TherapyR01CA251792 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI David Jonathan Sher, Jing Wang · 2022 to 2026
$2.5M
Optimal Decision Making in Radiotherapy Using Panomics AnalyticsR01CA233487 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EL NAQA, ISSAM M. · 2019 to 2023
$2.4M
Real-time prostate lesion tracking during SBRTR01EB027898 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI HANNAN, RAQUIBUL, WANG, JING · 2019 to 2022
$1.4M
NCI NIH HHS R01 CA233487NCI NIH HHS R01 CA251792NCI NIH HHS R01 CA266803NCI NIH HHS R37 CA222215NIBIB NIH HHS R01 EB027898
6 · The paper itself

Abstract

Quantitative image analysis, also known as radiomics, aims to analyze large-scale quantitative features extracted from acquired medical images using hand-crafted or machine-engineered feature extraction approaches. Radiomics has great potential for a variety of clinical applications in radiation oncology, an image-rich treatment modality that utilizes computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) for treatment planning, dose calculation, and image guidance. A promising application of radiomics is in predicting treatment outcomes after radiotherapy such as local control and treatment-related toxicity using features extracted from pretreatment and on-treatment images. Based on these individualized predictions of treatment outcomes, radiotherapy dose can be sculpted to meet the specific needs and preferences of each patient. Radiomics can aid in tumor characterization for personalized targeting, especially for identifying high-risk regions within a tumor that cannot be easily discerned based on size or intensity alone. Radiomics-based treatment response prediction can aid in developing personalized fractionation and dose adjustments. In order to make radiomics models more applicable across different institutions with varying scanners and patient populations, further efforts are needed to harmonize and standardize the acquisition protocols by minimizing uncertainties within the imaging data.

Indexed as

NeoplasmsRadiation OncologyHumansMagnetic Resonance ImagingPositron-Emission TomographyTomography, X-Ray Computed

Identifiers

PMID37331780
PMCPMC11214660
OpenAlexW4380925807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.