Evidence map›Paper›PMID 37330910›Full record

ArticleCell reports2023

Loss of PBAF promotes expansion and effector differentiation of CD8

Arjun Kharel, Jian Shen, Ryan Brown, Yao Chen, Christine Nguyen, Donia Alson, Theresa Bluemn, Jie Fan, Kexin Gai, Bin Zhang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Regulators of CD8Nature reviews. Immunology · 2026
    Review
  5. BRD9 at the crossroads of splicing, chromatin remodeling, and hematopoiesis.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. The role of the polybromo-associated BAF complex in development.Biochemistry and cell biology = Biochimie et biologie cellulaire · 2025
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Arjun KharelDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Jian ShenDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Ryan BrownDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, USA.
Yao ChenShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Christine NguyenBlood Research Institute, Versiti, Milwaukee, WI, USA; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, USA.
Donia AlsonBlood Research Institute, Versiti, Milwaukee, WI, USA.
Theresa BluemnBlood Research Institute, Versiti, Milwaukee, WI, USA; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
Jie FanDepartment of Medicine/Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Kexin GaiDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Bin ZhangDepartment of Medicine/Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Department of Microbiology-Immunology, Northwestern University, Chicago, IL, USA.
Matthew KudekBlood Research Institute, Versiti, Milwaukee, WI, USA.
Nan ZhuBlood Research Institute, Versiti, Milwaukee, WI, USA; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
Weiguo CuiDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Blood Research Institute, Versiti, Milwaukee, WI, USA; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address: weiguo.cui@northwestern.edu.
Northwestern University · USMedical College of Wisconsin · USVersiti Blood Center of Wisconsin · USShanghai Jiao Tong University · CN

Funding

Medical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7M
Phenotypic, Functional and Transcriptional Heterogeneity in T Cell ExhaustionR01AI148403 · NIAID · VERSITI WISCONSIN, INC. · PI WEIGUO CUI · 2020 to 2026
$3.1M
NIAID NIH HHS R01 AI148403NIGMS NIH HHS T32 GM080202
6 · The paper itself

Abstract

During chronic viral infection and cancer, it has been established that a subset of progenitor CD8

Indexed as

MelanomaVirus DiseasesAnimalsCD8-Positive T-LymphocytesCell DifferentiationChromosomal Proteins, Non-HistoneHumansMicePersistent InfectionTranscription FactorsChromosomal Proteins, Non-HistoneSWI-SNF-B chromatin-remodeling complexTranscription FactorsCD8(+) T cell differentiationCP: ImmunologyepigeneticsexhaustionimmunotherapyPBAFSWI/SNF

Identifiers

PMID37330910
PMCPMC10592487
OpenAlexW4380985608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.