Trial reportEuropean journal of applied physiology2023
Effects of muscle fatigue on exercise-induced hamstring muscle damage: a three-armed randomized controlled trial.
Trial report in European journal of applied physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Velocity-Dependent Stress Changes in the Hamstring Muscle-Tendon Complex: A Study Using Human Cadavers.Translational sports medicine · 2026Article
- A new conceptual framework for managing hamstring injury risk in soccer - implementing a data-informed approach: a narrative review.Biology of sport · 2026Review
- Antioxidant Defense and Redox Signaling in Elite Soccer Players: Insights into Muscle Function, Recovery, and Training Adaptations.Antioxidants (Basel, Switzerland) · 2025Review
- Metabolic contributions to hamstring muscle damage during maximal, high-speed eccentric exercise in males.Physiological reports · 2025Article
- Overlaps of Skeletal Muscle Fatigue and Skeletal Muscle Damage: The Muscle Injury Continuum.Sports medicine - open · 2025Review
- Article
- Acute fatigue-induced alterations in hamstring muscle properties after repeated Nordic hamstring exercises.Science progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHamstring injuries in soccer reportedly increase towards the end of the matches' halves as well as with increased match frequency in combination with short rest periods, possibly due to acute or residual fatigue. Therefore, this study aimed to investigate the effects of acute and residual muscle fatigue on exercise-induced hamstring muscle damage.
methodsA three-armed randomized-controlled trial, including 24 resistance-trained males, was performed allocating subjects to either a training group with acute muscle fatigue + eccentric exercise (AF/ECC); residual muscle fatigue + eccentric exercise (RF/ECC) or a control group with only eccentric exercise (ECC). Muscle stiffness, thickness, contractility, peak torque, range of motion, pain perception, and creatine kinase were assessed as muscle damage markers pre, post, 1 h post, and on the consecutive three days.
resultsSignificant group × time interactions were revealed for muscle thickness (p = 0.02) and muscle contractility parameters radial displacement (D
conclusionHamstring muscle damage was comparable between the three groups. However, the AF/ECC group resulted in the same amount of muscle damage while accumulating significantly less muscle work during the protocol of the damage exercise.
trial registrationThis study was preregistered in the international trial registration platform (WHO; registration number: DRKS00025243).
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