Evidence map›Paper›PMID 37330430›Full record

ArticleBreast cancer research and treatment2023

Validating the PROMIS cognitive function short form in cancer survivors.

Ashley M Henneghan, Kathleen Van Dyk, Xingtao Zhou, Raeanne C Moore, James C Root, Tim A Ahles, Zev M Nakamura, Jeanne Mandeblatt, Patricia A Ganz

Open access · greenAbstract read
In one paragraph

Article in Breast cancer research and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Accounting for unmet needs resulting from cancer-related cognitive impairment.Journal of cancer survivorship : research and practice · 2026
    Article
  5. Article
  6. Work challenges and cancer-related cognitive impairment: level of education accounts for unmet needs beyond cognitive impairment severity.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  7. The impact of social determinants of health on mental and behavioral health trajectories of breast cancer survivors: A longitudinal cohort study.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2026
    Article
  8. Article
  9. Article
  10. Observational
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  12. Review
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  14. Incidence and predictors of immune checkpoint inhibitor treatment-related cognitive impairment in a racial and ethnic diverse population.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  15. Review
  16. Article
  17. The MASCC COG-IMPACT: An unmet needs assessment for cancer-related cognitive impairment impact developed by the Multinational Association of Supportive Care in Cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Ashley M Henneghan *School of Nursing, University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0000-0002-6733-1926
Kathleen Van Dyk *Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA. KVanDyk@mednet.ucla.edu.ORCID http://orcid.org/0000-0003-1500-930X
Xingtao ZhouGeorgetown Lombardi Comprehensive Cancer Center Georgetown University, Washington, DC, USA.
Raeanne C MooreDepartment of Psychiatry, University of California San Diego, San Diego, CA, USA.
James C RootMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Tim A AhlesMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Zev M NakamuraDepartment of Psychiatry, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
Jeanne MandeblattGeorgetown Lombardi Comprehensive Cancer Center Georgetown University, Washington, DC, USA.
Patricia A GanzJonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA, USA.
Georgetown University · USMemorial Sloan Kettering Cancer Center · USUniversity of California, Los Angeles · USThe University of Texas at Austin · USUniversity of California San Diego · USUniversity of North Carolina at Chapel Hill · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
OLDER BREAST CANCER PATIENTS: RISK FOR COGNITIVE DECLINER01CA129769 · NCI · GEORGETOWN UNIVERSITY · PI AHLES, TIM ALAN, MANDELBLATT, JEANNE · 2009 to 2020
$7.3M
Bio-behavioral Research At The Intersection of Cancer and AgingR35CA197289 · NCI · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE · 2015 to 2021
$6.2M
Cognitive Aging, Alzheimers disease, and Cancer-related Cognitive DeclineR01AG068193 · NIA · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE, SAYKIN, ANDREW J · 2020 to 2023
$2.8M
Cognitive Functioning After Breast Cancer TreatmentR01CA109650 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GANZ, PATRICIA A. · 2006 to 2010
$2.2M
Brain Health in Breast Cancer Survivors: Interaction of Menopause and Endocrine TherapyK08CA241337 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DYK, KATHLEEN · 2019 to 2023
$925k
Heterogeneity in biological, physical, and cognitive aging in older breast cancer survivors and controlsR56AG068086 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CARROLL, JUDITH E, MANDELBLATT, JEANNE · 2021 to 2021
$886k
Defining Cognitive Patient Reported Outcomes of Breast Cancer Survivors in the Context of Everyday Functioning and Quality of LifeR21NR020497 · NINR · UNIVERSITY OF TEXAS AT AUSTIN · PI HENNEGHAN, ASHLEY M. · 2023 to 2024
$447k
Brain Connectivity and Self-Reported Cancer Related Cognitive ImpairmentK01NR018970 · NINR · UNIVERSITY OF TEXAS AT AUSTIN · PI HENNEGHAN, ASHLEY M. · 2020 to 2022
$312k
Biobehavioral Contributors to Cognition in Breast Cancer SurvivorsF31NR015707 · NINR · UNIVERSITY OF TEXAS AT AUSTIN · PI HENNEGHAN, ASHLEY M. · 2016 to 2017
$50k
NCI NIH HHS K08 CA241337NCI NIH HHS K08CA241337NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA109650NCI NIH HHS R01CA109650NCI NIH HHS R01 CA129769NCI NIH HHS R01CA129769NCI NIH HHS R35 CA197289NCI NIH HHS R35CA197289NIA NIH HHS R01 AG068193NIA NIH HHS R01AG068193NIA NIH HHS R56 AG068086NIA NIH HHS R56AG068086NINR NIH HHS F31 NR015707NINR NIH HHS F31NR015707NINR NIH HHS K01 NR018970NINR NIH HHS K01NR018970NINR NIH HHS R21 NR020497
6 · The paper itself

Abstract

purposeThe Patient-Reported Outcome Measurement Information System Cognitive Function Short Form 8a  (PROMIS Cog) could provide a shorter, useful alternative to the often used Functional Assessment of Cancer Therapy - Cognition (FACT-Cog) in research and clinical care. This study aimed to determine the convergent validity and internal reliability of the PROMIS Cog in 3 separate samples of breast cancer survivors and to explore clinical cut points.

methodsData from three samples of breast cancer survivors were used for this secondary analysis. Convergent validity was determined by evaluating correlation strength among the derived PROMIS Cog and measures of depression, anxiety, stress, fatigue, sleep, loneliness, the FACT-Cog . Clinical cut-points for the PROMIS Cog were determined by plotting the receiver operating characteristic curves.

results3 samples of breast cancer survivors (N = 471, N = 132, N = 90) were included. Absolute values of correlations demonstrating convergent validity ranged from 0.21 to 0.82, p's < 0.001, and were comparable to correlations with the full FACT-Cog 18 item perceived cognitive impairments (PCI) scale. ROC curve plots indicated a clinical cut off < 34 for the combined sample.

conclusionThe 8-item PROMIS Cog demonstrated good convergent validity and internal reliability in breast cancer survivors, comparable to the 18-item FACT-Cog PCI. The PROMIS Cog 8a is a brief self-report measure that can be easily incorporated into cancer-related cognitive impairment research designs or used in clinical settings.

Indexed as

Breast NeoplasmsCancer SurvivorsCognitionFemaleHumansPsychometricsQuality of LifeReproducibility of ResultsSelf ReportSurveys and QuestionnairesCancer-related cognitive impairmentConvergent validityInternal reliabilityPROMIS cognitionSelf-report

Identifiers

PMID37330430
PMCPMC10729147
OpenAlexW4381054514

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.