Trial reportBrain stimulation
Participant perceptions of changes in psychosocial domains following participation in an adaptive deep brain stimulation trial.
Trial report in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Implantable Neuromodulation Devices in Psychiatry: Human Fidelity and Implementation Challenges.The American journal of psychiatry · 2026Article
- Cognitive trajectories in Parkinson's disease patients, a review on the impact of subthalamic deep brain stimulation (STN-DBS) and emerging adaptive strategies.Translational psychiatry · 2026Review
- Ethical Guidance for Investigational Implantable Neural Device Studies: Recommendations for Researchers and Research Ethics Committees.Neuromodulation : journal of the International Neuromodulation Society · 2026Review
- Beyond the Numbers: Quantitative and qualitative analysis of quality of life after deep brain stimulation for OCD.PloS one · 2026Article
- Public Perceptions of Neurotechnologies Used to Target Mood, Memory, and Motor Symptoms.Device · 2025Article
- Deep brain stimulation and Parkinson disease: a bibliometric and visual analysis (1993-2023).Neurosurgical review · 2025Article
- Article
- Is the Treatment Worse than the Disease?: Key Stakeholders' Views about the Use of Psychiatric Electroceutical Interventions for Treatment-Resistant Depression.Neuroethics · 2025Article
- Ethical considerations for integrating multimodal computer perception and neurotechnology.Frontiers in human neuroscience · 2024Article
- Identity Theft, Deep Brain Stimulation, and the Primacy of Post-trial Obligations.The Hastings Center report · 2024Article
- The Potential Harms of Speculative Neuroethics Research.AJOB neuroscienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundThere has been substantial controversy in the neuroethics literature regarding the extent to which deep brain stimulation (DBS) impacts dimensions of personality, mood, and behavior. OBJECTIVE/HYPOTHESIS: Despite extensive debate in the theoretical literature, there remains a paucity of empirical data available to support or refute claims related to the psychosocial changes following DBS.
methodsA mixed-methods approach was used to examine the perspectives of patients who underwent DBS regarding changes to their personality, authenticity, autonomy, risk-taking, and overall quality of life.
resultsPatients (n = 21) who were enrolled in adaptive DBS trials for Parkinson's disease, essential tremor, obsessive-compulsive disorder, Tourette's syndrome, or dystonia participated. Qualitative data revealed that participants, in general, reported positive experiences with alterations in what was described as 'personality, mood, and behavior changes.' The majority of participants reported increases in quality of life. No participants reported 'regretting the decision to undergo DBS.' CONCLUSION(S): The findings from this patient sample do not support the narrative that DBS results in substantial adverse changes to dimensions of personality, mood, and behavior. Changes reported as "negative" or "undesired" were few in number, and transient in nature.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.