Evidence map›Paper›PMID 37329848›Full record

ArticleInternational journal for parasitology. Drugs and drug resistance2023

Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates.

Haddijatou Mbye, Fatoumata Bojang, Fatou Kene Jaiteh, Aminata Jawara, Bekai Njie, Simon Correa, Umberto D'Alessandro, Alfred Amambua-Ngwa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal for parasitology. Drugs and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Haddijatou MbyeMedical Research Council at London School of Hygiene and Tropical Medicine, Fajara, P. O. Box 273, Banjul, the Republic of the Gambia; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Legon, P. O Box LG 54, Accra, Ghana.
Fatoumata BojangMedical Research Council at London School of Hygiene and Tropical Medicine, Fajara, P. O. Box 273, Banjul, the Republic of the Gambia.
Fatou Kene JaitehMedical Research Council at London School of Hygiene and Tropical Medicine, Fajara, P. O. Box 273, Banjul, the Republic of the Gambia.
Aminata JawaraMedical Research Council at London School of Hygiene and Tropical Medicine, Fajara, P. O. Box 273, Banjul, the Republic of the Gambia.
Bekai NjieMedical Research Council at London School of Hygiene and Tropical Medicine, Fajara, P. O. Box 273, Banjul, the Republic of the Gambia.
Simon CorreaMedical Research Council at London School of Hygiene and Tropical Medicine, Fajara, P. O. Box 273, Banjul, the Republic of the Gambia.
Umberto D'AlessandroMedical Research Council at London School of Hygiene and Tropical Medicine, Fajara, P. O. Box 273, Banjul, the Republic of the Gambia.
Alfred Amambua-NgwaMedical Research Council at London School of Hygiene and Tropical Medicine, Fajara, P. O. Box 273, Banjul, the Republic of the Gambia. Electronic address: angwa@mrc.gm.
MRC Unit the Gambia · GMUniversity of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of resistance to deployed antimalarial drugs is inevitable and needs prompt and continuous discovery of novel candidate drugs. Therefore, the antimalarial activity of 125 compounds from the Medicine for Malaria Ventures (MMV) pathogen box was determined. Combining standard IC

Indexed as

AntimalarialsMalariaMalaria, FalciparumDrug DiscoveryHumansPlasmodium falciparumAntimalarialsAntimalarial drug susceptibilityMalariaMedicine for Malaria Venture (MMV)Pathogen boxPlasmodium falciparum

Identifiers

PMID37329848
PMCPMC10394470
OpenAlexW4380052282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.