Evidence map›Paper›PMID 37329635›Full record

ArticleThe Journal of surgical research2023

Identifying Young Adults at High Risk for Weight Gain Using Machine Learning.

Jacqueline A Murtha, Jen Birstler, Lily Stalter, Dawda Jawara, Bret M Hanlon, Lawrence P Hanrahan, Matthew M Churpek, Luke M Funk

Abstract read
In one paragraph

Article in The Journal of surgical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Deep Learning-Based Obesity Identification System for Young Adults Using Smartphone Inertial Measurements.International journal of environmental research and public health · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacqueline A MurthaDepartment of Surgery, University of Wisconsin, Madison, Wisconsin.
Jen BirstlerDepartment of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin.
Lily StalterDepartment of Surgery, University of Wisconsin, Madison, Wisconsin.
Dawda JawaraDepartment of Surgery, University of Wisconsin, Madison, Wisconsin.
Bret M HanlonDepartment of Surgery, University of Wisconsin, Madison, Wisconsin; Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin.
Lawrence P HanrahanDepartment of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Matthew M ChurpekDepartment of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin; Department of Medicine, University of Wisconsin, Madison, Wisconsin.
Luke M FunkDepartment of Surgery, University of Wisconsin, Madison, Wisconsin; Department of Surgery, William S. Middleton Memorial VA, Madison, Wisconsin. Electronic address: funk@surgery.wisc.edu.

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
TRAINING IN NUTRITIONT32DK007665 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI GUY E GROBLEWSKI, Chi- Liang Eric Yen · 1993 to 2026
$9.2M
Using Machine Learning for Early Recognition and Personalized Treatment of Acute Kidney InjuryR01DK126933 · NIDDK · UNIVERSITY OF CHICAGO · PI CHURPEK, MATTHEW MICHAEL, KOYNER, JAY L · 2021 to 2025
$3.4M
Using causal machine learning for personalized treatment recommendations in critically ill patientsR01HL157262 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Matthew Michael Churpek · 2021 to 2026
$3.1M
Sepsis Early Prediction and Subphenotype Illumination Study (SEPSIS)R01GM123193 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI CHURPEK, MATTHEW MICHAEL · 2017 to 2021
$1.9M
Impact of Financing on Outcomes of Methadone MaintenanceR01DA015060 · NIDA · RMC RESEARCH CORPORATION · PI DECK, DENNIS D · 2002 to 2004
$1.4M
Addressing Disparities in Bariatric Surgery outcomes for Medicaid PatientsR21MD012655 · NIMHD · UNIVERSITY OF WISCONSIN-MADISON · PI FUNK, LUKE M · 2018 to 2019
$421k
Identifying and Addressing Barriers to Bariatric Surgery within VAIK2HX002064 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI FUNK, LUKE M · 2018 to 2020
–
HSRD VA IK2 HX002064NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373NHLBI NIH HHS R01 HL157262NIDA NIH HHS R01 DA015060NIDDK NIH HHS R01 DK126933NIDDK NIH HHS T32 DK007665NIGMS NIH HHS R01 GM123193NIMHD NIH HHS R21 MD012655
6 · The paper itself

Abstract

introductionWeight gain among young adults continues to increase. Identifying adults at high risk for weight gain and intervening before they gain weight could have a major public health impact. Our objective was to develop and test electronic health record-based machine learning models to predict weight gain in young adults with overweight/class 1 obesity.

methodsSeven machine learning models were assessed, including three regression models, random forest, single-layer neural network, gradient-boosted decision trees, and support vector machine (SVM) models. Four categories of predictors were included: 1) demographics; 2) obesity-related health conditions; 3) laboratory data and vital signs; and 4) neighborhood-level variables. The cohort was split 60:40 for model training and validation. Area under the receiver operating characteristic curves (AUC) were calculated to determine model accuracy at predicting high-risk individuals, defined by ≥ 10% total body weight gain within 2 y. Variable importance was measured via generalized analysis of variance procedures.

resultsOf the 24,183 patients (mean [SD] age, 32.0 [6.3] y; 55.1% females) in the study, 14.2% gained ≥10% total body weight. Area under the receiver operating characteristic curves varied from 0.557 (SVM) to 0.675 (gradient-boosted decision trees). Age, sex, and baseline body mass index were the most important predictors among the models except SVM and neural network.

conclusionsOur machine learning models performed similarly and had modest accuracy for identifying young adults at risk of weight gain. Future models may need to incorporate behavioral and/or genetic information to enhance model accuracy.

Indexed as

Machine LearningWeight GainAdultElectronic Health RecordsFemaleHumansMaleNeural Networks, ComputerObesityYoung AdultAdultMachine learningObesityWeight gainYoung

Identifiers

PMID37329635
PMCPMC10524852

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.