ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2023
Comparison of mortality rate and septic and aseptic revisions in total hip arthroplasties for osteoarthritis and femoral neck fracture: an analysis of the German Arthroplasty Registry.
Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Antithrombotic prophylaxis following total hip arthroplasty: a level I Bayesian network meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024Pooled it
- Risk factors for liner wear and head migration in total hip arthroplasty: a systematic review.Scientific reports · 2023Pooled it
- Comparison of Hospital Mortality and Risk Factors in Conservative and Surgical Treatment of Pyogenic Vertebral Osteomyelitis: A Nationwide Analysis of 49,951 Cases in Germany.Global spine journal · 2026Article
- Increased Risk of Complications in Total Hip Arthroplasty (THA) of Femoral Neck Fracture (FNF): A Comparative Meta-Analysis of THA Outcomes in FNF and Osteoarthritis.Hip & pelvis · 2026Review
- Factors associated with aseptic loosening after primary total hip arthroplasty: A systematic review and meta-analysis.World journal of orthopedics · 2026Article
- MIPPO Combined With NCB.PP for Treating Vancouver Type B Femoral Periprosthetic Fractures.Orthopaedic surgery · 2026Article
- Socioeconomic burden of septic re-revision surgeries for periprosthetic joint infections in Europe - a comprehensive analysis of re-revision costs.Journal of bone and joint infection · 2026Article
- Short-Term Complications of Revision Total Hip Arthroplasty of the Acetabular, Femoral, or Both Components: A National Surgical Quality Improvement Program Database Study.Arthroplasty today · 2025Article
- Surgical timing and clinical factor predicting in-hospital mortality in older adults with hip fractures: a neuronal network analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025Observational
- Synovial fluid viscosity with synovial fluid cell count, valuable diagnostic marker of prosthetic joint infections.Scientific reports · 2025Article
- Combining systemic inflammation biomarkers with traditional prognostic factors to predict surgical site infections in elderly hip fracture patients: a risk factor analysis and dynamic nomogram development.Journal of orthopaedic surgery and research · 2025Article
- Difference in early all-cause mortality among patients having hip arthroplasty a Swedish perioperative registry study 2013-2022.Journal of orthopaedic surgery and research · 2024Article
- Pseudotumor from ceramic-on-ceramic total hip arthroplasty.International journal of surgery case reports · 2024Article
- Midterm survival and risk factor analysis in patients with pyogenic vertebral osteomyelitis: a retrospective study of 155 cases.Frontiers in surgery · 2024Article
- Clinical effects of different center of rotation reconstructions in total hip arthroplasty after femoral neck fractures: a cohort study including a follow-up analysis on patient's mobility and daily living ability.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023Article
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Authors and funding
9 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIndications for total hip arthroplasties (THA) differ from primary osteoarthritis (OA), which allows elective surgery through femoral neck fractures (FNF), which require timely surgical care. The aim of this investigation was to compare mortality and revisions in THA for primary OA and FNF.
methodsData collection for this study was performed using the German Arthroplasty Registry (EPRD) with analysis THA for the treatment of FNF and OA. Cases were matched 1:1 according to age, sex, body mass index (BMI), cementation, and the Elixhauser score using Mahalanobis distance matching.
resultsOverall 43,436 cases of THA for the treatment of OA and FNF were analyzed in this study. Mortality was significantly increased in FNF, with 12.6% after 1 year and 36.5% after 5 years compared with 3.0% and 18.7% in OA, respectively (p < 0.0001). The proportion for septic and aseptic revisions was significantly increased in FNF (p < 0.0001). Main causes for an aseptic failure were mechanical complications (OA: 1.1%; FNF: 2.4%; p < 0.0001) and periprosthetic fractures (OA: 0.2%; FNF: 0.4%; p = 0.021). As influencing factors for male patients with septic failure (p < 0.002), increased BMI and Elixhauser comorbidity score and diagnosis of fracture (all p < 0.0001) were identified. For aseptic revision surgeries, BMI, Elixhauser score, and FNF were influencing factors (p < 0.0001), while all cemented and hybrid cemented THA were associated with a risk reduction for aseptic failure within 90 days after surgery (p < 0.0001).
conclusionIn femoral neck fractures treated with THA, a significant higher mortality, as well as septic and aseptic failure rate, was demonstrated compared with prosthesis for the therapy of osteoarthritis. Increased Elixhauser comorbidity score and BMI are the main influencing factors for development of septic or aseptic failure and can represent a potential approach for prevention measures. LEVEL OF EVIDENCE: Level III, Prognostic.
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