Evidence map›Paper›PMID 37329412›Full record

ArticleCardiology and therapy2023

Endovascular Revascularization and Outcomes of Critical Limb-Threatening Ischemia in Trinidad and Tobago: The EVENT Pilot Study-Challenges in a Limited-Resource, Caribbean Setting.

Dave Harnanan, Sangeeta Parbhu, Lemuel Pran, Ilecia Baboolal, Patrick Harnarayan, Vijay Naraynsingh, Naveen Seecheran

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cardiology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05547022 (Critical Limb Ischemia in Trinidad and Tobago- A Series of 157 Endovascular Limb Salvage Attempts in Patients With CLTI), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05547022 completednot on this map

Critical Limb Ischemia in Trinidad and Tobago- A Series of 157 Endovascular Limb Salvage Attempts in Patients With CLTI

TypeobservationalSponsorNaveen SeecheranRan2018 to 2022Enrolled157ConditionsLimb Salvage Rates With Endovascular TherapyArmsEndovascular revascularisation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dave HarnananDepartment of Clinical Surgical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Sangeeta ParbhuDepartment of Clinical Surgical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Lemuel PranDepartment of Surgery, North Central Regional Health Authority, Mount Hope, Trinidad and Tobago.
Ilecia BaboolalDepartment of Surgery, North Central Regional Health Authority, Mount Hope, Trinidad and Tobago.
Patrick HarnarayanDepartment of Clinical Surgical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Vijay NaraynsinghDepartment of Clinical Surgical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Naveen SeecheranDepartment of Clinical Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago. Naveen.Seecheran@sta.uwi.edu.ORCID http://orcid.org/0000-0002-7779-0181
University of the West Indies · TT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis retrospective study investigated major adverse limb events (MALE) and mortality outcomes in critical limb-threatening ischemia (CLTI) patients with tissue loss after an endovascular revascularization-first (EVR-1st) strategy.

methodsMALE and mortality were assessed in 157 consecutive patients with CLTI and tissue loss from June 2019 to June 2022 at the Eric Williams Medical Sciences Complex, Trinidad and Tobago.

results157 patients underwent the EVR-1st strategy, of whom 20 were pivoted to immediate surgical revascularization (SR). Of the remaining 137 patients, successful EVR was achieved in 112, giving a procedural success of 82% and an all-comer overall success of 71%. The mortality and MALE rates were 2.7% and 8.9% at 2 years, respectively. Males and patients with previous major amputations were at significantly higher risk for MALE (p values of 0.016 and 0.018, respectively). There was a statistically significant difference in successful EVR for both Rutherford-Baker (RB) 5 (minor) and RB 6 (major) classifications: 63 (56%) vs. 5 (20%) and 49 (44%) vs. 20 (80%), both with a p value of 0.01. There were no differences in successful EVR amongst Wound, Ischemia, Foot Infection (WIfI) clinical stages. There were no differences in successful EVR amongst the Trans-Atlantic Inter-Society Consensus (TASC II) classifications.

conclusionsThis study may prove clinically informative and applicable for an EVR-1st management strategy for high-risk patients with CLTI in a limited-resource, Caribbean setting. TRIAL REGISTRATION NUMBER: NCT05547022 (retrospectively registered).

Indexed as

Critical limb-threatening ischemia (CLTI)Endovascular revascularization (EVR)Major adverse limb event (MALE)Peripheral arterial disease (PAD)Peripheral vascular disease (PVD)

Identifiers

PMID37329412
PMCPMC10423177
OpenAlexW4381052437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.