ArticleAnnals of clinical and translational neurology2023
Nomogram to predict unfavorable outcome of endovascular thrombectomy for large ischemic core.
Article in Annals of clinical and translational neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Identification of signal-based gait features and blood analytes associated with stroke status and walking speed in mild acute ischemic stroke.BMC neurology · 2026Article
- Internal Capsule Involvement Explains the Prognostic Impact of ASPECTS after Endovascular Thrombectomy for Large-Core Infarction.Translational stroke research · 2026Article
- OCTA-Derived Retinal Biomarkers and Infarct Topography Improve Etiologic Classification of Recent Single Subcortical Infarction: A Nomogram Model.CNS neuroscience & therapeutics · 2026Article
- Impact of cavernous internal carotid artery tortuosity on technical and clinical outcomes in mechanical thrombectomy for acute ischemic stroke: a single-center retrospective study.Frontiers in neurology · 2026Article
- Predicting early severe midline shift in acute ischemic stroke Within 24 h of endovascular thrombectomy.Neuroradiology · 2026Article
- Radiomics to predict PNI in ESCC.Abdominal radiology (New York) · 2025Article
- Nomogram-Based Prediction of 3-Month Unfavorable Outcome and Early Neurological Deterioration After Endovascular Thrombectomy in Acute Ischemic Stroke.Therapeutics and clinical risk management · 2025Article
- An externally validated prognostic model for critically ill patients with traumatic brain injury.Annals of clinical and translational neurology · 2024Article
- Endovascular thrombectomy versus medical management on outcomes with infarct volumes more than 70 mL.Annals of clinical and translational neurology · 2024Observational
- Application of radiomics in ischemic stroke.The Journal of international medical research · 2024Review
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17 authors.
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Abstract
objectiveThe prognosis for patients presenting with a large ischemic core (LIC) following endovascular thrombectomy is relatively poor. This study aimed to construct and validate a nomogram for predicting 3-month unfavorable outcome in patients with anterior circulation occlusion-related LIC who underwent endovascular thrombectomy.
methodsA retrospective training cohort and a prospective validation cohort of patients with a large ischemic core were studied. The diffusion weighted imaging related radiomic features and pre-thrombectomy clinical features were collected. After the selection of relevant features, a nomogram predicting modified Rankin Scale score of 3-6 as an unfavorable outcome was established. The discriminatory value of the nomogram was evaluated with a receiver operating characteristic curve.
resultsA total of 140 patients (mean age 66.3 ± 13.4 years, 35% female) were included in this study, consisting of a training cohort (n = 95) and a validation cohort (n = 45). The percentage of patients with an mRS scores of 0-2 was 30%, 0-3 was 40.7%, and 32.9% were dead. Age, National Institute of Health Stroke Scale (NIHSS) score, and two radiomic features, Maximum2DDiameterColumn and Maximum2DDiameterSlice, were identified as factors associated with unfavorable outcome in the nomogram. The nomogram demonstrated an area under the curve of 0.892 (95% confidence interval [CI], 0.812-0.947) in the training dataset and 0.872 (95% CI, 0.739-0.953) in the validation dataset.
interpretationThis nomogram, which includes age, NIHSS score, Maximum2DDiameterColumn, and Maximum2DDiameterSlice, may predict the risk of unfavorable outcome in patients with LIC caused by anterior circulation occlusion.
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