Evidence map›Paper›PMID 37328773›Full record

ReviewVirology journal2023

Acute and post-acute sequelae of SARS-CoV-2 infection: a review of risk factors and social determinants.

Chumeng Wang, Akshara Ramasamy, Monica Verduzco-Gutierrez, W Michael Brode, Esther Melamed

Abstract readReview
In one paragraph

Review in Virology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chumeng Wang *Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Akshara Ramasamy *Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Monica Verduzco-GutierrezDepartment of Physical Medicine and Rehabilitation, University of Texas at San Antonio, San Antonio, TX, USA.
W Michael BrodeDepartment of Internal Medicine, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Esther MelamedDepartment of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA. Esther.melamed@austin.utexas.edu.

Funding

Alcohol's Impact on the Gut-Brain Axis in a Mouse Model of Multiple SclerosisK08AA027837 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI MELAMED, ESTHER · 2020 to 2024
$971k
NIAAA NIH HHS K08 AA027837NIH HHS NIAAA K08 T26-1616-11
6 · The paper itself

Abstract

SARS-CoV-2 infection leading to Coronavirus Disease 2019 (COVID-19) has caused more than 762 million infections worldwide, with 10-30% of patients suffering from post-acute sequelae of SARS-CoV-2 infections (PASC). Initially thought to primarily affect the respiratory system, it is now known that SARS-CoV-2 infection and PASC can cause dysfunction in multiple organs, both during the acute and chronic stages of infection. There are also multiple risk factors that may predispose patients to worse outcomes from acute SARS-CoV-2 infection and contribute to PASC, including genetics, sex differences, age, reactivation of chronic viruses such as Epstein Barr Virus (EBV), gut microbiome dysbiosis, and behavioral and lifestyle factors, including patients' diet, alcohol use, smoking, exercise, and sleep patterns. In addition, there are important social determinants of health, such as race and ethnicity, barriers to health equity, differential cultural perspectives and biases that influence patients' access to health services and disease outcomes from acute COVID-19 and PASC. Here, we review risk factors in acute SARS-CoV-2 infection and PASC and highlight social determinants of health and their impact on patients affected with acute and chronic sequelae of COVID-19.

Indexed as

COVID-19Epstein-Barr Virus InfectionsDisease ProgressionFemaleHerpesvirus 4, HumanHumansMalePost-Acute COVID-19 SyndromeRisk FactorsSARS-CoV-2Social Determinants of HealthCOVID-19Long-COVIDPASCRisk factorsSocial determinants

Identifiers

PMID37328773
PMCPMC10276420

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.