ArticleAmerican journal of clinical dermatology2023
Targeting Inflammation in Acne: Current Treatments and Future Prospects.
Article in American journal of clinical dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Current state of research on acupuncture for acne: a scoping review.Frontiers in physiology · 2025Pooled it
- Biologic-biologic and biologic-JAK inhibitor combination therapy in refractory systemic autoinflammatory diseases.Seminars in arthritis and rheumatism · 2026Observational
- Italian Translation, Cultural Adaptation and Clinical Application of the ACNE-Q: Patient-Reported Outcome Measure in Mild-to-Moderate Facial Acne.Aesthetic plastic surgery · 2026Article
- Ferrous lactate-loaded hydrogels induce iron-dependent non-canonical ferroptosis inMaterials today. Bio · 2026Article
- Mediating Effect of Sleep Quality on the Association Between Psychological Stress and Acne Vulgaris in Chinese College Students: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Diosmetin, an active ingredient of Schizonepeta tenuifolia, alleviates acne by regulating inflammation and oxidative stress.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Human and Marine Host Defense Peptides for Healthy Skin.Marine drugs · 2026Review
- Evaluation of the Efficacy of Plasma Shower and 585 Nm Q-Switched Laser in the Treatment of Mild to Moderate Acne Vulgaris.Journal of cosmetic dermatology · 2026Article
- Integrating Dermocosmetics Into Acne Care in Latin America.Journal of cosmetic dermatology · 2026Review
- Nitric oxide-releasing hyaluronic acid as an antibacterial and immunomodulatory acne therapeutic.RSC advances · 2026Article
- Keratinocyte-Associated Biomarkers Reveal Pathogenic Mechanisms in Acne.FASEB bioAdvances · 2026Article
- Knowledge, attitudes, and practices regarding acne among university students.Scientific reports · 2026Article
- Risk factors for acne vulgaris among rosacea patients: a cross-sectional study.Frontiers in public health · 2026Article
- Targeting macrophage polarization: mechanisms and potential of mesenchymal stromal/stem cells therapy in acne treatment- a narrative review.Frontiers in immunology · 2026Review
- Potential role of insulin-like growth factor 1 and growth hormone in acneiform eruptions: evidence from a rat model of acromegaly.Journal of endocrinological investigation · 2026Article
- Clinical Evaluation Indicators and Efficacy Assessment Methods in Acne: A Narrative Review.Journal of inflammation research · 2026Review
- A Retrospective Analysis of the Clinical Response and Safety of Radiofrequency Microneedling Treatment in Managing Acne Vulgaris.Aesthetic surgery journal. Open forum · 2026Article
- Efficacy and Safety of Human Skin Microbiome-Derived Strains as Topical Treatment for Acne: An In Vitro and In Vivo Study.Journal of Korean medical science · 2025Article
- Rebalancing the Skin: The Microbiome, Acne Pathogenesis, and the Future of Natural and Synthetic Therapies.Molecules (Basel, Switzerland) · 2025Review
- Skin microbiome engineering: Challenges and opportunities in skin diseases treatment.iMetaOmics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acne is a common, chronic inflammatory condition affecting millions of people worldwide, with significant negative impact on quality of life and mental health. Acne is characterized by comedones, inflammatory papules, pustules, and nodulocystic lesions, with long-lasting sequelae including scarring and dyspigmentation, the latter of which is more common in skin of color. The four main pillars of acne pathophysiology include alteration of sebum production and concentration, hyperkeratinization of the follicular unit, Cutibacterium acnes strains, and an inflammatory immune response. Newer research has provided greater insight into these pathophysiologic categories. This greater understanding of acne pathogenesis has led to numerous new and emerging treatment modalities. These modalities include combinations of existing treatments, repurposing of existing agents historically used for other conditions, new topical treatments, novel antibiotics, topical and oral probiotics, and various procedural devices. This article will provide an overview of emerging treatments of acne and their link to our current and improved understanding of acne pathogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.