Evidence map›Paper›PMID 37328139›Full record

ArticleNanomedicine : nanotechnology, biology, and medicine2023

Functional attachment of primary neurons and glia on radiopaque implantable biomaterials for nerve repair.

Kendell M Pawelec, Jeremy M L Hix, Erik M Shapiro

Abstract read
In one paragraph

Article in Nanomedicine : nanotechnology, biology, and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Tantalum-Based Nanomaterials: From Properties to Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kendell M PawelecMichigan State University, Dept Radiology, East Lansing, MI 48823, United States of America. Electronic address: paweleck@msu.edu.
Jeremy M L HixMichigan State University, Dept Radiology, East Lansing, MI 48823, United States of America; Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48823, United States of America.
Erik M ShapiroMichigan State University, Dept Radiology, East Lansing, MI 48823, United States of America. Electronic address: shapir86@msu.edu.

Funding

Radiopaque 3D printed tissue engineered scaffolds for nerve generationR01EB029418 · NIBIB · MICHIGAN STATE UNIVERSITY · PI Erik Shapiro · 2021 to 2026
$3.2M
NIBIB NIH HHS R01 EB029418
6 · The paper itself

Abstract

Repairing peripheral nerve injuries remains a challenge, even with use of auxiliary implantable biomaterial conduits. After implantation the location or function of polymeric devices cannot be assessed via clinical imaging modalities. Adding nanoparticle contrast agents into polymers can introduce radiopacity enabling imaging using computed tomography. Radiopacity must be balanced with changes in material properties impacting device function. In this study radiopaque composites were made from polycaprolactone and poly(lactide-co-glycolide) 50:50 and 85:15 with 0-40 wt% tantalum oxide (TaO

Indexed as

Biocompatible MaterialsNeurogliaNerve RegenerationNeuronsPolymersProstheses and ImplantsBiocompatible MaterialsPolymersMyelinationNanoparticleNerve repairRadiopaqueX-ray computed tomography

Identifiers

PMID37328139
PMCPMC10527527

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.