Evidence map›Paper›PMID 37327328›Full record

ArticleScience advances2023

Battery-free and AI-enabled multiplexed sensor patches for wound monitoring.

Xin Ting Zheng, Zijie Yang, Laura Sutarlie, Moogaambikai Thangaveloo, Yong Yu, Nur Asinah Binte Mohamed Salleh, Jiah Shin Chin, Ze Xiong, David Lawrence Becker, Xian Jun Loh and 2 more

Abstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

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  9. Ionic-Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  17. [Researches and clinical translation of smart dressings].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xin Ting ZhengInstitute of Materials Research and Engineering (IMRE), Agency for Science Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore 138634, Republic of Singapore.ORCID 0000-0002-1431-0929
Zijie YangDepartment of Materials Science and Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Republic of Singapore.ORCID 0009-0002-7917-1883
Laura SutarlieInstitute of Materials Research and Engineering (IMRE), Agency for Science Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore 138634, Republic of Singapore.ORCID 0000-0003-4110-2831
Moogaambikai ThangavelooLee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore 308232, Republic of Singapore.ORCID 0000-0001-5404-8622
Yong YuInstitute of Materials Research and Engineering (IMRE), Agency for Science Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore 138634, Republic of Singapore.ORCID 0000-0002-6271-707X
Nur Asinah Binte Mohamed SallehInstitute of Materials Research and Engineering (IMRE), Agency for Science Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore 138634, Republic of Singapore.
Jiah Shin ChinLee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore 308232, Republic of Singapore.ORCID 0000-0001-9820-3516
Ze XiongInstitute for Health Innovation and Technology (iHealthtech), National University of Singapore, MD6, 14 Medical Drive, Singapore 117599, Republic of Singapore.ORCID 0000-0003-4620-6066
David Lawrence BeckerLee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore 308232, Republic of Singapore.ORCID 0000-0002-9300-0899
Xian Jun LohInstitute of Materials Research and Engineering (IMRE), Agency for Science Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore 138634, Republic of Singapore.
Benjamin C K TeeDepartment of Materials Science and Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Republic of Singapore.ORCID 0000-0002-9180-4105
Xiaodi SuInstitute of Materials Research and Engineering (IMRE), Agency for Science Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore 138634, Republic of Singapore.ORCID 0000-0003-2164-4588

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is a dynamic process with multiple phases. Rapid profiling and quantitative characterization of inflammation and infection remain challenging. We report a paper-like battery-free in situ AI-enabled multiplexed (PETAL) sensor for holistic wound assessment by leveraging deep learning algorithms. This sensor consists of a wax-printed paper panel with five colorimetric sensors for temperature, pH, trimethylamine, uric acid, and moisture. Sensor images captured by a mobile phone were analyzed by neural network-based machine learning algorithms to determine healing status. For ex situ detection via exudates collected from rat perturbed wounds and burn wounds, the PETAL sensor can classify healing versus nonhealing status with an accuracy as high as 97%. With the sensor patches attached on rat burn wound models, in situ monitoring of wound progression or severity is demonstrated. This PETAL sensor allows early warning of adverse events, which could trigger immediate clinical intervention to facilitate wound care management.

Indexed as

BurnsWound HealingAlgorithmsAnimalsMachine LearningRats

Identifiers

PMID37327328
PMCPMC10275586

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.