Evidence map›Paper›PMID 37326999›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2023

Application of 4-D ultrasound-derived regional strain and proteomics analysis in

Frederick W Damen, Daniel P Gramling, Dorothy Ahlf Wheatcraft, Robert Y Wilpan, Mauro W Costa, Craig J Goergen

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Frederick W DamenWeldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States.ORCID 0000-0001-9213-5508
Daniel P GramlingWeldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States.
Dorothy Ahlf WheatcraftGaithersburg, Maryland, United States.
Robert Y WilpanJackson Laboratory, Bar Harbor, Maine, United States.ORCID 0000-0002-5772-3176
Mauro W CostaJackson Laboratory, Bar Harbor, Maine, United States.ORCID 0000-0003-3579-8625
Craig J GoergenWeldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States.ORCID 0000-0001-8883-7953

Funding

Indiana Medical Scientist/Engineer Training ProgramT32GM077229 · NIGMS · INDIANA UNIVERSITY INDIANAPOLIS · PI GASTON, BENJAMIN, HERBERT, BRITTNEY-SHEA · 2008 to 2022
$6.0M
Indiana Medical Scientist/Engineer Training ProgramT32GM148382 · NIGMS · INDIANA UNIVERSITY INDIANAPOLIS · PI Benjamin Gaston, Emily K Sims · 2023 to 2026
$3.9M
Interdisciplinary Bioengineering Training in Diabetes ResearchT32DK101001 · NIDDK · PURDUE UNIVERSITY · PI EVANS-MOLINA, CARMELLA, VOYTIK-HARBIN, SHERRY L · 2013 to 2022
$1.6M
Spatial Analysis of Cardiac Disease using Murine Four-Dimensional UltrasoundF30HL145980 · NHLBI · PURDUE UNIVERSITY · PI DAMEN, FREDERICK W · 2019 to 2021
$141k
NHLBI NIH HHS F30 HL145980NIDDK NIH HHS T32 DK101001NIGMS NIH HHS T32 GM077229NIGMS NIH HHS T32 GM148382
6 · The paper itself

Abstract

The comprehensive characterization of cardiac structure and function is critical to better understanding various murine models of cardiac disease. We demonstrate here a multimodal analysis approach using high-frequency four-dimensional ultrasound (4DUS) imaging and proteomics to explore the relationship between regional function and tissue composition in a murine model of metabolic cardiomyopathy (

Indexed as

CardiomyopathiesVentricular Dysfunction, LeftAnimalsCross-Sectional StudiesHomeobox Protein Nkx-2.5MaleMiceProteomicsUltrasonographyHomeobox Protein Nkx-2.5Nkx2-5 protein, mousecontractilityfour-dimensional ultrasoundhypertrophyleft ventriclestrain mapping

Identifiers

PMID37326999
PMCPMC10393333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.