Evidence map›Paper›PMID 37326806›Full record

ArticleAlcohol, clinical & experimental research2023

Changes in alcohol consumption reported on routine healthcare screenings are associated with changes in depression symptoms.

Kevin A Hallgren, Helen E Jack, Malia Oliver, Douglas Berger, Jennifer F Bobb, Daniel R Kivlahan, Katharine A Bradley

Open access · bronzeAbstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kevin A HallgrenDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-8386-3984
Helen E JackDivision of General Internal Medicine, University of Washington, Seattle, Washington, USA.
Malia OliverKaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
Douglas BergerDivision of General Internal Medicine, University of Washington, Seattle, Washington, USA.
Jennifer F BobbKaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
Daniel R KivlahanCenter of Innovation for Veteran-Centered and Value-Driven Care, Health Services Research and Development, Veteran Affairs Puget Sound HealthCare System, Seattle, Washington, USA.
Katharine A BradleyKaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
Kaiser Permanente Washington Health Research Institute · USUniversity of Washington · USHealth Services Research & Development · US

Funding

Understanding practical alcohol measures in primary care to prepare for measurement-based care: Scaled EHR measures of alcohol use and DSM-5 AUD symptomsR33AA028073 · NIAAA · UNIVERSITY OF WASHINGTON · PI HALLGREN, KEVIN A. · 2021 to 2023
$1.3M
Practice facilitation and supervision to strengthen depression treatment in primary care in ZimbabweK23MH129420 · NIMH · UNIVERSITY OF WASHINGTON · PI Helen Elizabeth Jack · 2022 to 2026
$922k
Developing a tool to assess, provide feedback, and facilitate discussion of mechanisms of change in frontline addiction treatmentK01AA024796 · NIAAA · UNIVERSITY OF WASHINGTON · PI HALLGREN, KEVIN A. · 2016 to 2020
$870k
Understanding practical alcohol measures in primary care to prepare for measurement-based care: Scaled EHR measures of alcohol use and DSM-5 AUD symptomsR21AA028073 · NIAAA · UNIVERSITY OF WASHINGTON · PI HALLGREN, KEVIN A. · 2019 to 2020
$439k
NIAAA NIH HHS K01 AA024796NIAAA NIH HHS K01AA024796NIAAA NIH HHS R21 AA028073NIAAA NIH HHS R21AA028073NIAAA NIH HHS R33 AA028073NIAAA NIH HHS R33AA028073NIMH NIH HHS K23 MH129420NIMH NIH HHS K23MH129420
6 · The paper itself

Abstract

backgroundThe Alcohol Use Disorders Identification Test-Consumption version (AUDIT-C) has been robustly validated as a point-in-time screen for unhealthy alcohol use, but less is known about the significance of changes in AUDIT-C scores from routine screenings over time. Unhealthy alcohol use and depression commonly co-occur, and changes in drinking often co-occur with changes in depression symptoms. We assess the associations between changes in AUDIT-C scores and changes in depression symptoms reported on brief screens completed in routine care.

methodsThe study sample included 198,335 primary care patients who completed two AUDIT-C screens 11 to 24 months apart and the Patient Health Questionnaire-2 (PHQ-2) depression screen on the same day as each AUDIT-C. Both screening measures were completed as part of routine care within a large health system in Washington state. AUDIT-C scores were categorized to reflect five drinking levels at both time points, resulting in 25 subgroups with different change patterns. For each of the 25 subgroups, within-group changes in the prevalence of positive PHQ-2 depression screens were characterized using risk ratios (RRs) and McNemar's tests.

resultsPatient subgroups with increases in AUDIT-C risk categories generally experienced increases in the prevalence of positive depression screens (RRs ranging from 0.95 to 2.00). Patient subgroups with decreases in AUDIT-C risk categories generally experienced decreases in the prevalence of positive depression screens (RRs ranging from 0.52 to 1.01). Patient subgroups that did not have changes in AUDIT-C risk categories experienced little or no change in the prevalence of positive depression screens (RRs ranging from 0.98 to 1.15).

conclusionsAs hypothesized, changes in alcohol consumption reported on AUDIT-C screens completed in routine care were associated with changes in depression screening results. Results support the validity and clinical utility of monitoring changes in AUDIT-C scores over time as a meaningful measure of changes in drinking.

Indexed as

alcohol usechanges in drinkingdepressionmeasurement-based caremental healthprimary carescreening

Identifiers

PMID37326806
PMCPMC10330324
OpenAlexW4380869975

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.